PDB entry 7lqk

View 7lqk on RCSB PDB site
Description: Crystal structure of the R375A mutant of LeuT
Class: transport protein
Keywords: Transporter, Leucine transporter, TRANSPORT PROTEIN
Deposited on 2021-02-13, released 2021-05-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Na(+):neurotransmitter symporter (Snf family)
    Species: Aquifex aeolicus (strain VF5) [TaxId:224324]
    Gene: snf, aq_2077
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67854
      • engineered mutation (374)
    Domains in SCOPe 2.08: d7lqka_
  • Heterogens: ALA, NA, BOG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7lqkA (A:)
mevkrehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmw
iewamgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfai
kflvglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinv
silirgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkd
pgvwiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisip
aavaffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaim
qpmiafledelklsakhavlwtaaivffsahlvmflnksldemdfwagtigvvffgltel
iiffwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeeth
wtvwitrfyiiglflfltflvflaerrrnhesagtlvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >7lqkA (A:)
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpeppptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirg
iskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwia
avgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaff
gvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiaf
ledelklsakhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwi
fgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwit
rfyiiglflfltflvflaerrrnhe