PDB entry 7lo4
View 7lo4 on RCSB PDB site
Description: SARS-CoV-2 spike receptor-binding domain with a G485R mutation in complex with human ACE2
Class: viral protein
Keywords: viral protein/hydrolase, complex, VIRAL PROTEIN
Deposited on
2021-02-09, released
2021-03-31
The last revision prior to the SCOPe 2.07 freeze date was dated
2021-03-31, with a file datestamp of
2021-03-26.
Experiment type: XRAY
Resolution: 2.47 Å
R-factor: N/A
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Processed angiotensin-converting enzyme 2
Species: Homo sapiens [TaxId:9606]
Gene: ACE2, UNQ868/PRO1885
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d7lo4a_ - Chain 'B':
Compound: Spike protein S1
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: S, 2
Database cross-references and differences (RAF-indexed):
- Uniprot P0DTC2 (0-197)
- engineered mutation (152)
- expression tag (198-199)
Domains in SCOPe 2.07: d7lo4b1, d7lo4b2 - Heterogens: NAG, EDO, ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>7lo4A (A:)
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspya
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>7lo4B (B:)
tnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcf
tnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyl
yrlfrksnlkpferdisteiyqagstpcngverfncyfplqsygfqptngvgyqpyrvvv
lsfellhapatvcgpkksen