PDB entry 7lhm

View 7lhm on RCSB PDB site
Description: Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal
Class: cytosolic protein
Keywords: hCRBPII, Q4A, Q38L, isomerization, retinal, all-trans-retinal, rhodopsin, bacteriorhodopsin, CYTOSOLIC PROTEIN
Deposited on 2021-01-25, released 2021-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-14, with a file datestamp of 2021-04-09.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (3)
      • engineered mutation (18)
      • engineered mutation (28)
      • engineered mutation (37)
      • engineered mutation (39)
      • engineered mutation (50)
      • engineered mutation (52)
      • engineered mutation (57)
      • engineered mutation (107)
    Domains in SCOPe 2.08: d7lhma_
  • Chain 'B':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (3)
      • engineered mutation (18)
      • engineered mutation (28)
      • engineered mutation (37)
      • engineered mutation (39)
      • engineered mutation (50)
      • engineered mutation (52)
      • engineered mutation (57)
      • engineered mutation (107)
    Domains in SCOPe 2.08: d7lhmb_
  • Heterogens: RET, ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lhmA (A:)
trdangtwemesnenfegwmkaldidfalrkiavrltltlvidqdgdnfkvkctstfwny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7lhmB (B:)
trdangtwemesnenfegwmkaldidfalrkiavrltltlvidqdgdnfkvkctstfwny
dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
cgdqvcrqvfkkk