PDB entry 7lfe

View 7lfe on RCSB PDB site
Description: SARS-CoV-2 Main protease immature form - F2X Entry Library E03 fragment
Class: hydrolase
Keywords: 3cl, protease, sars, sars-cov-2, covid, main protease, HYDROLASE
Deposited on 2021-01-16, released 2021-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2.79 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-308)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7lfea1, d7lfea2
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-308)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7lfeb_
  • Heterogens: XWS, PEG, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7lfeA (A:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >7lfeA (A:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7lfeB (B:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >7lfeB (B:)
gfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllirk
snhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyngs
psgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegnf
ygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynyep
ltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqcs