PDB entry 7ldl
View 7ldl on RCSB PDB site
Description: Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability
Class: viral protein,hydrolase/inhibitor
Keywords: COVID-19, SARS-CoV-2, 3CLpro, coronavirus, main protease, kinetics, SARS, VIRAL PROTEIN, Hydrolase-Hydrolase Inhibitor complex, HYDROLASE, HYDROLASE-INHIBITOR complex
Deposited on
2021-01-13, released
2021-07-07
The last revision prior to the SCOPe 2.08 freeze date was dated
2021-07-07, with a file datestamp of
2021-07-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 3C-like proteinase
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: rep, 1a-1b
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d7ldla_ - Chain 'B':
Compound: 3C-like proteinase
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: rep, 1a-1b
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d7ldlb_ - Heterogens: XV4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>7ldlA (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllir
ksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegn
fygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc
sgvtfq
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>7ldlB (B:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllir
ksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegn
fygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc
sgvtfq