PDB entry 7l9x

View 7l9x on RCSB PDB site
Description: structure of vps4b in complex with an allele-specific covalent inhibitor
Deposited on 2021-01-05, released 2021-04-14
The last revision was dated 2021-04-28, with a file datestamp of 2021-04-23.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vacuolar protein sorting-associated protein 4B
    Species: Homo sapiens [TaxId:9606]
    Gene: VPS4B, SKD1, VPS42, MIG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75351 (Start-445)
      • engineered mutation (136)
  • Heterogens: XQV, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7l9xA (A:)
shmsstspnlqkaidlaskaaqedkagnyeealqlyqhavqyflhvvkyeaqgdkakqsi
rakcteyldraeklkeylknkekkaqkpvkegqpspadekgndsdgegesddpekkklqn
qlqgaivierpnvkwscvaglegakealkeavilpikfphlftgkrtpwrgillfgppgt
gksylakavateannstffsisssdlvskwlgeseklvknlfqlarenkpsiifideids
lcgsrseneseaarrikteflvqmqgvgvdndgilvlgatnipwvldsairrrfekriyi
plpepharaamfklhlgttqnslteadfrelgrktdgysgadisiivrdalmqpvrkvqs
athfkkvrgpsradpnhlvddlltpcspgdpgaiemtwmdvpgdkllepvvsmsdmlrsl
sntkptvnehdllklkkftedfgqeg

    Sequence, based on observed residues (ATOM records):
    >7l9xA (A:)
ierpnvkwscvaglegakealkeavilpikfphlftgkrtpwrgillfgppgtgksylak
avateannstffsisssseklvknlfqlarenkpsiifideidslcseaarrikteflvq
mqvdndgilvlgatnipwvldsairrrfekriyiplpepharaamfklhlgttqnsltea
dfrelgrktdgysgadisiivrdalmqpvrkvqsathfkkvrgpsradpnhlvddlltpc
spgdpgaiemtwmdvpgdkllepvvsmsdmlrslsntkptvnehdllklkkftedfgqeg