PDB entry 7l9h

View 7l9h on RCSB PDB site
Description: crystal structure of human arh3-d77a bound to magnesium and adp-ribose
Deposited on 2021-01-04, released 2021-04-28
The last revision was dated 2021-07-21, with a file datestamp of 2021-07-16.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribose glycohydrolase ARH3
    Species: Homo sapiens [TaxId:9606]
    Gene: ADPRS, ADPRHL2, ARH3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX46 (3-365)
      • expression tag (0-2)
      • engineered mutation (79)
  • Chain 'B':
    Compound: ADP-ribose glycohydrolase ARH3
    Species: Homo sapiens [TaxId:9606]
    Gene: ADPRS, ADPRHL2, ARH3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX46 (3-365)
      • expression tag (0-2)
      • engineered mutation (79)
  • Chain 'C':
    Compound: ADP-ribose glycohydrolase ARH3
    Species: Homo sapiens [TaxId:9606]
    Gene: ADPRS, ADPRHL2, ARH3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX46 (3-365)
      • expression tag (0-2)
      • engineered mutation (79)
  • Chain 'D':
    Compound: ADP-ribose glycohydrolase ARH3
    Species: Homo sapiens [TaxId:9606]
    Gene: ADPRS, ADPRHL2, ARH3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX46 (3-365)
      • expression tag (0-2)
      • engineered mutation (79)
  • Heterogens: AR6, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7l9hA (A:)
gphmaaaamaaaagggagaarslsrfrgclagallgdcvgsfyeahdtvdltsvlrhvqs
lepdpgtpgsertealyytadtamaralvqsllakeafdevdmahrfaqeykkdpdrgyg
agvvtvfkkllnpkcrdvfeparaqfngkgsygnggamrvagislayssvqdvqkfarls
aqlthasslgyngailqalavhlalqgesssehflkqllghmedlegdaqsvldarelgm
eerpyssrlkkigelldqasvtreevvselgngiaafesvptaiycflrcmepdpeipsa
fnslqrtliysislggdtdtiatmagaiagayygmdqvpeswqqscegyeetdilaqslh
rvfqks

    Sequence, based on observed residues (ATOM records):
    >7l9hA (A:)
agaarslsrfrgclagallgdcvgsfyevdltsvlrhvqsltealyytadtamaralvqs
llakeafdevdmahrfaqeykkdpdrgygagvvtvfkkllnpkcrdvfeparaqfngkgs
ygnggamrvagislayssvqdvqkfarlsaqlthasslgyngailqalavhlalqgesss
ehflkqllghmedlegdaqsvldarelgmeerpyssrlkkigelldqasvtreevvselg
ngiaafesvptaiycflrcmepdpeipsafnslqrtliysislggdtdtiatmagaiaga
yygmdqvpeswqqscegyeetdilaqslhrvfqk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7l9hB (B:)
gphmaaaamaaaagggagaarslsrfrgclagallgdcvgsfyeahdtvdltsvlrhvqs
lepdpgtpgsertealyytadtamaralvqsllakeafdevdmahrfaqeykkdpdrgyg
agvvtvfkkllnpkcrdvfeparaqfngkgsygnggamrvagislayssvqdvqkfarls
aqlthasslgyngailqalavhlalqgesssehflkqllghmedlegdaqsvldarelgm
eerpyssrlkkigelldqasvtreevvselgngiaafesvptaiycflrcmepdpeipsa
fnslqrtliysislggdtdtiatmagaiagayygmdqvpeswqqscegyeetdilaqslh
rvfqks

    Sequence, based on observed residues (ATOM records):
    >7l9hB (B:)
agaarslsrfrgclagallgdcvgsfyeahltsvlrhvqsealyytadtamaralvqsll
akeafdevdmahrfaqeykkdpdrgygagvvtvfkkllnpkcrdvfeparaqfngkgsyg
nggamrvagislayssvqdvqkfarlsaqlthasslgyngailqalavhlalqgessseh
flkqllghmedlegdaqsvldarelgmeerpyssrlkkigelldqasvtreevvselgng
iaafesvptaiycflrcmepdpeipsafnslqrtliysislggdtdtiatmagaiagayy
gmdqvpeswqqscegyeetdilaqslhrvfq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7l9hC (C:)
gphmaaaamaaaagggagaarslsrfrgclagallgdcvgsfyeahdtvdltsvlrhvqs
lepdpgtpgsertealyytadtamaralvqsllakeafdevdmahrfaqeykkdpdrgyg
agvvtvfkkllnpkcrdvfeparaqfngkgsygnggamrvagislayssvqdvqkfarls
aqlthasslgyngailqalavhlalqgesssehflkqllghmedlegdaqsvldarelgm
eerpyssrlkkigelldqasvtreevvselgngiaafesvptaiycflrcmepdpeipsa
fnslqrtliysislggdtdtiatmagaiagayygmdqvpeswqqscegyeetdilaqslh
rvfqks

    Sequence, based on observed residues (ATOM records):
    >7l9hC (C:)
agaarslsrfrgclagallgdcvgsfyevdltsvlrhvqsletealyytadtamaralvq
sllakeafdevdmahrfaqeykkdpdrgygagvvtvfkkllnpkcrdvfeparaqfngkg
sygnggamrvagislayssvqdvqkfarlsaqlthasslgyngailqalavhlalqgess
sehflkqllghmedlegdaqsvldarelgmeerpyssrlkkigelldqasvtreevvsel
gngiaafesvptaiycflrcmepdpeipsafnslqrtliysislggdtdtiatmagaiag
ayygmdqvpeswqqscegyeetdilaqslhrvfqks

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7l9hD (D:)
gphmaaaamaaaagggagaarslsrfrgclagallgdcvgsfyeahdtvdltsvlrhvqs
lepdpgtpgsertealyytadtamaralvqsllakeafdevdmahrfaqeykkdpdrgyg
agvvtvfkkllnpkcrdvfeparaqfngkgsygnggamrvagislayssvqdvqkfarls
aqlthasslgyngailqalavhlalqgesssehflkqllghmedlegdaqsvldarelgm
eerpyssrlkkigelldqasvtreevvselgngiaafesvptaiycflrcmepdpeipsa
fnslqrtliysislggdtdtiatmagaiagayygmdqvpeswqqscegyeetdilaqslh
rvfqks

    Sequence, based on observed residues (ATOM records):
    >7l9hD (D:)
agaarslsrfrgclagallgdcvgsfyeahdtvdltsvlrhvealyytadtamaralvqs
llakeafdevdmahrfaqeykkdpdrgygagvvtvfkkllnpkcrdvfeparaqfngkgs
ygnggamrvagislayssvqdvqkfarlsaqlthasslgyngailqalavhlalqgesss
ehflkqllghmedlegdaqsvldarelgmeerpyssrlkkigelldqasvtreevvselg
ngiaafesvptaiycflrcmepdpeipsafnslqrtliysislggdtdtiatmagaiaga
yygmdqvpeswqqscegyeetdilaqslhrvfqk