PDB entry 7l6c

View 7l6c on RCSB PDB site
Description: Crystal Structure of Enoyl-[acyl-carrier-protein] reductase InhA from Mycobacterium abscessus in complex with NAD
Class: oxidoreductase
Keywords: SSGCID, Enoyl-[acyl-carrier-protein] reductase, InhA, MAB_2722c, NAD, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, OXIDOREDUCTASE
Deposited on 2020-12-23, released 2021-01-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) [TaxId:561007]
    Gene: MAB_2722c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7l6ca_
  • Chain 'B':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) [TaxId:561007]
    Gene: MAB_2722c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7l6cb_
  • Chain 'C':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) [TaxId:561007]
    Gene: MAB_2722c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7l6cc_
  • Chain 'D':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) [TaxId:561007]
    Gene: MAB_2722c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7l6cd_
  • Heterogens: NAD, EDO, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7l6cA (A:)
mahhhhhhmagllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritq
rlpkpaplleldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdap
fadvskgfhisafsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvn
rfvareagkvgvrsnlvaagpirtlamsaivggalgdeagqqmqlleegwdqrapigwdm
kdptpvaktvcallsdwlpattgdiifadggahtqll

    Sequence, based on observed residues (ATOM records): (download) 
    >7l6cA (A:)
gllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritqrlpkpaplle
ldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdapfadvskgfhi
safsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvnrfvareagkv
gvrsnlvaagpirtlamsaivggalgdeagqqmqlleegwdqrapigwdmkdptpvaktv
callsdwlpattgdiifadggahtqll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7l6cB (B:)
mahhhhhhmagllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritq
rlpkpaplleldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdap
fadvskgfhisafsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvn
rfvareagkvgvrsnlvaagpirtlamsaivggalgdeagqqmqlleegwdqrapigwdm
kdptpvaktvcallsdwlpattgdiifadggahtqll

    Sequence, based on observed residues (ATOM records): (download) 
    >7l6cB (B:)
agllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritqrlpkpapll
eldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdapfadvskgfh
isafsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvnrfvareagk
vgvrsnlvaagpirtlamsaivggalgdeagqqmqlleegwdqrapigwdmkdptpvakt
vcallsdwlpattgdiifadggahtqll

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7l6cC (C:)
mahhhhhhmagllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritq
rlpkpaplleldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdap
fadvskgfhisafsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvn
rfvareagkvgvrsnlvaagpirtlamsaivggalgdeagqqmqlleegwdqrapigwdm
kdptpvaktvcallsdwlpattgdiifadggahtqll

    Sequence, based on observed residues (ATOM records): (download) 
    >7l6cC (C:)
gllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritqrlpkpaplle
ldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdapfadvskgfhi
safsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvnrfvareagkv
gvrsnlvaagpirtlamsaivggalgdeagqqmqlleegwdqrapigwdmkdptpvaktv
callsdwlpattgdiifadggahtqll

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7l6cD (D:)
mahhhhhhmagllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritq
rlpkpaplleldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdap
fadvskgfhisafsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvn
rfvareagkvgvrsnlvaagpirtlamsaivggalgdeagqqmqlleegwdqrapigwdm
kdptpvaktvcallsdwlpattgdiifadggahtqll

    Sequence, based on observed residues (ATOM records): (download) 
    >7l6cD (D:)
gllegkrilvtgiitdssiafhiakvaqeqgaelvltgfdrlrlieritqrlpkpaplle
ldvqneehlgslagrisevigegnkldgvvhsigfmpqsgmgvnpffdapfadvskgfhi
safsysslakavlpvmnrggsivgmdfdptrampaynwmtvaksalesvnrfvareagkv
gvrsnlvaagpirtlamsaivalgdeagqqmqlleegwdqrapigwdmkdptpvaktvca
llsdwlpattgdiifadggahtqll