PDB entry 7kzc

View 7kzc on RCSB PDB site
Description: Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Class: immune system
Keywords: COVID19, SARS-CoV2, antibody, IMMUNE SYSTEM
Deposited on 2020-12-10, released 2021-02-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-09, with a file datestamp of 2021-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: Fab heavy chain of m396-B10 antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KZC (0-End)
    Domains in SCOPe 2.08: d7kzcc1, d7kzcc2
  • Chain 'D':
    Compound: Fab light chain of m396-B10 antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KZC (0-End)
    Domains in SCOPe 2.08: d7kzcd1, d7kzcd2
  • Chain 'H':
    Compound: Fab heavy chain of m396-B10 antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KZC (0-End)
    Domains in SCOPe 2.08: d7kzch1, d7kzch2
  • Chain 'L':
    Compound: Fab light chain of m396-B10 antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KZC (0-214)
    Domains in SCOPe 2.08: d7kzcl1, d7kzcl2
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7kzcC (C:)
qvqlqqsgaevkkpgssvkvsckasggtfstysiswvrqapgqglewmggiapshgfany
aqkfqgrvtittdeststaymelsslrsedtavyycardtatggmdvwgqgttvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >7kzcC (C:)
qvqlqqsgaevkkpgssvkvsckasstysiswvrqapgqglewmggrvtittdeststay
melsslrsedtavyycardtatggmdvwgqgttvtvssastkgpsvfplapstaalgclv
kdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkp
sntkvdkkvepk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7kzcD (D:)
syeltqppsvsvapgktaritcggnnigsksvhwyqqkpgqapvlvvyddsdrpsgiper
fsgsnsgntatltisrveagdeadyycqvwdtysdyvfgtgtkvtvlrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgecs

    Sequence, based on observed residues (ATOM records): (download) 
    >7kzcD (D:)
syeltqppsvsvapgktaritcggnnigsksvhwyqqkpgqapvlvvyddsdrpsgiper
fsgsnsgntatltisrveagdeadyycqvwdtysdyvfgtgtkvtvlrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7kzcH (H:)
qvqlqqsgaevkkpgssvkvsckasggtfstysiswvrqapgqglewmggiapshgfany
aqkfqgrvtittdeststaymelsslrsedtavyycardtatggmdvwgqgttvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >7kzcH (H:)
qvqlqqsgaevkkpgssvkvsckastfstysiswvrqapgqglewmgginyaqkfqgrvt
ittdeststaymelsslrsedtavyycardtgmdvwgqgttvtvssastkgpsvfplaps
skggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslg
tqtyicnvnhkpsntkvdkkvepks

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7kzcL (L:)
syeltqppsvsvapgktaritcggnnigsksvhwyqqkpgqapvlvvyddsdrpsgiper
fsgsnsgntatltisrveagdeadyycqvwdtysdyvfgtgtkvtvlrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgecs