PDB entry 7kwa

View 7kwa on RCSB PDB site
Description: structure of dcn1 bound to n-((4s,5s)-3-(aminomethyl)-7-ethyl-4-(4- fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1h-pyrazolo[3,4- b]pyridin-5-yl)-3-(trifluoromethyl)benzamide
Deposited on 2020-11-30, released 2021-07-14
The last revision was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 1.57 Å
R-factor: N/A
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Endolysin,DCN1-like protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCUN1D1, DCN1, DCUN1L1, RP42, SCCRO
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A097J809 (22-185)
      • expression tag (0-21)
      • conflict (75)
      • conflict (118)
      • conflict (167)
    • Uniprot Q96GG9 (186-383)
  • Heterogens: YHP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kwaA (A:)
mgsshhhhhhsqdlenlyfqgsmnifemlrideglrlkiykdtegyytigighlltksps
lnaakseldkaigrntngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrraa
linmvfqmgetgvagftnslrmlqqkrwdeaavnlaksrwynqtpnrtkrvittfrtgtw
dayknlrkkleqlynrykdpqdenkigidgiqqfcddlaldpasisvliiawkfraatqc
efskqefmdgmtelgcdsieklkaqipkmeqelkepgrfkdfyqftfnfaknpgqkgldl
emaiaywnlvlngrfkfldlwnkfllehhkrsipkdtwnllldfstmiaddmsnydeega
wpvliddfvefarpqiagtksttv

    Sequence, based on observed residues (ATOM records):
    >7kwaA (A:)
hsqdlenlyfqgsmnifemlrideglrlkiykdtegyytigighlltkspslnaakseld
kaigrntngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrraalinmvfqmg
etgvagftnslrmlqqkrwdeaavnlaksrwynqtpnrtkrvittfrtgtwdayknlrkk
leqlynrykdpqdenkigidgiqqfcddlaldpasisvliiawkfraatqcefskqefmd
gmtelgcdsieklkaqipkmeqelkepgrfkdfyqftfnfaknpgqkgldlemaiaywnl
vlngrfkfldlwnkfllehhkrsipkdtwnllldfstmiaddmsnydeegawpvliddfv
efarpqiagtks