PDB entry 7kvx

View 7kvx on RCSB PDB site
Description: Structure of hSTING in complex with novel carbocyclic pyrimidine CDN 1
Class: immune system
Keywords: immunotherapy, stimulator of interferon genes, cyclic dinucleotide, IMMUNE SYSTEM
Deposited on 2020-11-29, released 2021-06-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-09, with a file datestamp of 2021-06-04.
Experiment type: XRAY
Resolution: 2.48 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Stimulator of interferon genes protein
    Species: Homo sapiens [TaxId:9606]
    Gene: STING, LOC340061, hCG_1782396
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7kvxa_
  • Heterogens: X5J, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kvxA (A:)
ggsapaeisavcekgnfnvahglawsyyigylrlilpelqarirtynqhynnllrgavsq
rlyillpldcgvpdnlsmadpnirfldklpqqtgdragikdrvysnsiyellengqragt
cvleyatplqtlfamsqysqagfsredrleqaklfcrtlediladapesqnncrliayqe
paddssfslsqevlrhlrqeekeevtvgslktsavpststmsqepellisgmekplplrt
dfs

    Sequence, based on observed residues (ATOM records): (download) 
    >7kvxA (A:)
nfnvahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdn
lsmadpnirfldklpqqtgdragikdrvysnsiyellengqragtcvleyatplqtlfam
sqysqagfsredrleqaklfcrtlediladapesqnncrliayqepsfslsqevlrhlrq
e