PDB entry 7kvl

View 7kvl on RCSB PDB site
Description: SARS-CoV-2 Main protease immature form - FMAX Library E01 fragment
Class: hydrolase
Keywords: mPro, main protease, COVID-19, SARS-CoV-2, 3CL, HYDROLASE
Deposited on 2020-11-28, released 2020-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-308)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7kvla1, d7kvla2
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-308)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7kvlb_
  • Heterogens: X4P, PEG, DMS, SER, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kvlA (A:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >7kvlA (A:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7kvlB (B:)
gamsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedl
lirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlac
yngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdl
egnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamky
nyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvv
rqcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >7kvlB (B:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllir
ksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegn
fygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc