PDB entry 7kus

View 7kus on RCSB PDB site
Description: crystal structure of danio rerio histone deacetylase 10 h137a mutant in complex with n8-acetylspermidine (tetrahedral intermediate)
Deposited on 2020-11-25, released 2021-02-03
The last revision was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polyamine deacetylase HDAC10
    Species: Danio rerio [TaxId:7955]
    Gene: hdac10
    Database cross-references and differences (RAF-indexed):
    • Uniprot F1QCV2 (3-676)
      • expression tag (2)
      • conflict (25)
      • conflict (95)
      • engineered mutation (138)
      • conflict (155)
      • conflict (549)
      • conflict (587)
      • conflict (594)
      • conflict (597)
      • conflict (614)
      • conflict (647)
      • expression tag (677)
  • Heterogens: X54, PEG, EDO, ZN, K, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kusA (A:)
snaasgsalifdeemsrykllwtdpeceievperltvsyealrthglaqrckavpvrqat
eqeillahseeyleavkqtpgmnveelmafskkynavyfhqniyhcaklaagatlqlvds
vmkrevrngmalvrppghasqrsaangfcvfnnvafaalyakknynlnrilivdwdvhhg
qgiqycfeedpsvlyfswhryehqsfwpnlpesdyssvgkgkgsgfninlpwnkvgmtns
dylaaffhvllpvayefdpelvivsagfdsaigdpegemcalpeifahlthllmplaagk
mcvvleggynltslgqsvcqtvhsllgdptprisglgtacdsalesiqnvrnvqssywss
fkhlaqsetnpkrprldatnggpkessepasesnpkktaqdivwpeplkrmpasvrtvvv
pppgveltlpkncqhsgdisestakevqrirdkhfhdltdqnilrslgniisvldrmmrs
devcngcvvvsdlsvsvqcalqhaltepaervlvvyvgdgelpvktndgkvflvqictke
tedkcvnrltlclregesltagfmqallglilpvayefnpalvlgiveetaaktrlmrvw
ghmtcliqglargrmltllqgydkdlleltvsalsgasisplgplrapkpedvemmekqr
qrlqerwgllrctvsesw

    Sequence, based on observed residues (ATOM records):
    >7kusA (A:)
aasgsalifdeemsrykllwtdpeceievperltvsyealrthglaqrckavpvrqateq
eillahseeyleavkqtpgmnveelmafskkynavyfhqniyhcaklaagatlqlvdsvm
krevrngmalvrppghasqrsaangfcvfnnvafaalyakknynlnrilivdwdvhhgqg
iqycfeedpsvlyfswhryehqsfwpnlpesdyssvgkgkgsgfninlpwnkvgmtnsdy
laaffhvllpvayefdpelvivsagfdsaigdpegemcalpeifahlthllmplaagkmc
vvleggynltslgqsvcqtvhsllgdptprisglgtacdsalesiqnvrnvqssywssfk
hlaqsedivwpeplkrmpasvrtvvvpppgveltlpkncqhsdisestakevqrirdkhf
hdltdqnilrslgniisvldrmmrsdevcngcvvvsdlsvsvqcalqhaltepaervlvv
yvgdgelpvktndgkvflvqictketedkcvnrltlclregesltagfmqallglilpva
yefnpalvlgiveetrlmrvwghmtcliqglargrmltllqgydkdlleltvsalsgasi
splgprapkpedvemmekqrqrlqerwgllrctvsesw