PDB entry 7kra

View 7kra on RCSB PDB site
Description: cryo-em structure of saccharomyces cerevisiae er membrane protein complex bound to fab-dh4 in lipid nanodiscs
Deposited on 2020-11-19, released 2020-12-02
The last revision was dated 2020-12-09, with a file datestamp of 2020-12-04.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ER membrane protein complex subunit 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ER membrane protein complex subunit 2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: ER membrane protein complex subunit 3
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ER Membrane Protein Complex Subunit 4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: ER membrane protein complex subunit 5
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: ER membrane protein complex subunit 6
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Protein SOP4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Endoplasmic reticulum membrane protein complex subunit 10
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Fab DH4 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KRA
  • Chain 'J':
    Compound: Fab DH4 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KRA (Start-233)
  • Chain 'M':
    Compound: Unassigned helix
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KRA (0-End)
  • Chain 'N':
    Compound: Unassigned helix
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KRA (0-23)
  • Heterogens: NAG, X3P

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kraA (A:)
mkitctdlvyvfillflntscvqavfsddafitdwqlanlgpwekvipdsrdrnrvlils
nptetsclvssfnvssgqilfrnvlpftideiqldsndhnamvcvnsssnhwqkydlhdw
flleegvdnapsttilpqssylndqvsiknnelhildeqsklaewklelpqgfnkveyfh
redplalvlnvndtqymgfsangtelipvwqrdewltnvvdyavldvfdsrdvelnkdmk
aeldsnslwnaywlrlttnwnrlinllkenqfspgrvftkllaldakdttvsdlkfgfak
ilivlthdgfiggldmvnkgqliwkldleidqgvkmfwtdknhdelvvfshdghyltiev
tkdqpiiksrsplserktvdsvirlnehdhqylikfedkdhllfklnpgkntdvpivann
hssshifvtehdtngiygyiiendtvkqtwkkavnskekmvayskrettnlntlgitlgd
ksvlykylypnlaaylianeehhtitfnlidtitgeilitqehkdspdfrfpmdivfgey
wvvysyfssepvpeqklvvvelyesltpderlsnssdnfsydpltghinkpqfqtkqfif
peiiktmsiskttddittkaivmelengqityipklllnargkpaeemakdkkkefmatp
ytpvipindnfiithfrnllpgsdsqlisiptnlestsiicdlgldvfctritpsgqfdl
msptfekgkllitifvllvityfirpsvsnkklksqwlik

    Sequence, based on observed residues (ATOM records):
    >7kraA (A:)
vfsddafitdwqlanlgpwekvipdsrdrnrvlilsnptetsclvssfnvssgqilfrnv
lpftideiqldsnamvcvnsssnhwqkydlhdwflleegvdnapsttilpqssylndqvs
iknnelhildeqsklaewklelpqgfnkveyfhredplalvlnvndtqymgfsalipvwq
rdewltnvvdyavldvfdsslwnaywlrlttnwnrlinllkepgrvftkllalkdttvsd
lkfgfakilivlthdgfiggldmvnkgqliwkldleidqgvkmfwtdknhdelvvfshdg
hyltievtkdqpiiksrsplserktvdsvirlnehdhqylikfedkdhllfklnpgkssh
ifvtehdtngiygyiiendtvkqtwkkavnskekmvayskrettnlntlgitlgdksvly
kylypnlaaylianeehhtitfnlidtitgeilitqehkdspdfrfpmdivfgeywvvys
yfssepvpeqklvvvelyesltpderlsnssdnfsydpltghinkpqfqtkqfifpeiik
tmsiskttddittkaivmelengqityipklllnargkpaeemakdkkkefmatpytpvi
pindnfiithfrnllpgsdsqlisiptnlestsiicdlgldvfctritpsgqfdlmsptf
ekgkllitifvllvityfirpsvsnkklksqwli

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7kraB (B:)
mlkdlvreklltimntkaytqfnpeqllqlenemkiymksgdsaltegnyfflmemlfyv
lvyrnqdvdaqvvyntlrdrlgensykmvimkatllqingndkgaieylenllnddleye
tdfvtyvsiakkliaikttsknlsqesvlkevvaltdkfpldaelwwyaseiyfemgqfe
kacycleqvlcitpfnyacfgrlsetlyyealrskkqtktellekalknalrsvelsely
lkgwalvniisrelgrnkqndliklsasklkeisaksnnkdkitaelilnki

    Sequence, based on observed residues (ATOM records):
    >7kraB (B:)
kdlvreklltimntkaytqfnpeqllqlenemkiymksgdsaltegnyfflmemlfyvlv
yrnqdvdaqvvyntlrdrlgensykmvimkatllqingndkgaieylenllnddleyetd
fvtyvsiakkliaikttsknlsqesvlkevvaltdkfpldaelwwyaseiyfemgqfeka
cycleqvlcitpfnyacfgrlsetlyyealrskkqtktellekalknalrsvelselylk
gwalvniisrelgrnkqndliklsasklkeisaksnnkdkitaelilnki

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7kraC (C:)
mllddqlkywvllpisivmvltgvlkqyimtlitgssaneaqprvkltewqylqwaqlli
gnggnlssdafaakkeflvkdlteerhlakakqqdgsqagevpnpfndpsmsnammnmak
gnmasfipqtiimwwvnhffagfilmqlpfpltakfkemlqtgiicqdldvrwvssiswy
fisvlglnpvynliglndqdmgiqagiggpqgpqgppqsqvdkamhamandltiiqhetc
ldnveqrvlkqym

    Sequence, based on observed residues (ATOM records):
    >7kraC (C:)
llddqlkywvllpisivmvltgvlkqyimtlitgaqprvkltewqylqwaqllignggnl
ssdafaakkeflvkdltnmasfipqtiimwwvnhffagfilmqlpfpltakfkemlqtgi
icqdldvrwvssiswyfisvlglnpvynliglndqvdkamhamandltiiqhetcldnve
qrvlkqym

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7kraD (D:)
mseqepyewakhlldtkyiekyniqnsntlpsppgfegnsskgnvtrkqqdatsqttsla
qknqitvlqvqkawqialqpaksipmnifmsymsgtslqiipimtalmllsgpikaifst
rsafkpvlgnkatqsqvqtamfmyivfqgvlmyigyrklnsmglipnakgdwlpweriah
ynnglqwfsd

    Sequence, based on observed residues (ATOM records):
    >7kraD (D:)
ewakhlldtkyiekyniqmfmyivfqgvlmyigyrklnsmglipnakgdwlpweriahyn
nglqwfsd

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7kraE (E:)
msfvskllytvsalvlfhsgfssyefhhllklnslnnaqgaisklpkdimyetyaglilf
vlavftsfeklqylpiesndgkiisqgnylkeialnkatnvdnligsnpngeiiftpsfv
dvhmkrkicrewasntvkkekggsgsgenlyfqsgsgsdykddddkdykddddkdykddd
dk

    Sequence, based on observed residues (ATOM records):
    >7kraE (E:)
sfvskllytvsalvlfhsgfssyefhhllklnslnnaqglpkdimyetyaglilfvlavf
tsfeklqylpiesndgkiisqgnylkeialnkatnvdnligsnpngeiiftpsfvdvhmk
rkicrewas

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7kraF (F:)
mssneevftqinatanvvdnkkrllfvqdssalvlglvagflqiesvhgfiwflilynli
nviyivwicqlqpgkfyqsplhdiffesffreitgfvmawtfgyalig

    Sequence, based on observed residues (ATOM records):
    >7kraF (F:)
natanvvdnkkrllfvqdssalvlglvagflqiesvhgfiwflilynlinviyivwicql
qpgkfyqsplhdiffesffreitgfvmawtfgyal

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7kraG (G:)
mfsqivlllsafiyvasatarrgtikgrldlaasnitgfvstrtsfklyqignfsteypy
tsttmfqddegnfefanlplndgvnettyyvmypasmdfnlkpnriliefknlengtlql
nafknffgreyfpskditypeklqsmkvhpyitvellhkapirsylqarnvsifstgivg
nilnsrwklagvitlialvvfpiivekldpetaraireeakrkqrekyaavask

    Sequence, based on observed residues (ATOM records):
    >7kraG (G:)
arrgtikgrldlaasnitgfvstrtsfklyqignfsteypytsttmfqddegnfefanlp
lndgvnettyyvmypasmdfnlkpnriliefknlengtlqlnafknffgreyfpskdity
peklqsmkvhpyitvellhkapirsylqarn

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7kraH (H:)
mlvrllrvillasmvfcadilqlsysddakdaiplgtfeidstsdgnvtvttvniqdvev
sgeyclnaqiegkldmpcfsymklrtplkydlivdvdednevkqvslsydetndaitatv
rypeagptapvtklkkktktyadkkasknkdgstaqfeedeevkevswfqknwkmlllgl
liynfvagsakkqqqggagadqkte

    Sequence, based on observed residues (ATOM records):
    >7kraH (H:)
adilqlsysddakdaiplgtfeidstsdgnvtvttvniqdvevsgeyclnaqiegkldmp
cfsymklrtplkydlivdvdednevkqvslsydetndaitatvrypeagptapvtklkkk
tktya

  • Chain 'I':
    Sequence, based on SEQRES records:
    >7kraI (I:)
maqvqlqqwgagllkpsetlsltcavyggsfsgyywswirqppgkglewigeinhsgstn
ynpslksrvtisvdtsknqfslklssvtaadtavyycarglagrgyygsgsylrwgqgtl
vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscaaahhhhhhgaa
eqkliseedlngaa

    Sequence, based on observed residues (ATOM records):
    >7kraI (I:)
aqvqlqqwgagllkpsetlsltcavyggsfsgyywswirqppgkglewigeinhsgstny
nvdtsknqfslklssdtavyycarglagrgyygsgsylrwgqgtlvtvssastkgpsvfp
lgclvkdyfpepvtvswhtfpavllyslssvvticnvnhkpsntkvdkkv

  • Chain 'J':
    Sequence, based on SEQRES records:
    >7kraJ (J:)
lfaiplvvpfyshsaldvvmtqsplslpvtpgepasiscrssqtlmnrngnnfldwylqk
pgqspqlliylgsnrapgvpdrfsgsgsgtdftlrisrvepedvgvyycmqalqtpsfgg
gtkveirrtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsq
esvteqdskdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >7kraJ (J:)
dvvmtqsplslpvtpgepasiscrssqtlmnrngnnfldwylqkpgqspqlliylgsnra
pgvpdrfsgsgsgtdftlrisrvepedvgvyycmqalqtpsfgggtkveirrpsvfifpp
sdetasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskad
yekhkvyacevthqglsspvtksfnrgec

  • Chain 'M':
    Sequence, based on SEQRES records:
    >7kraM (M:)
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    Sequence, based on observed residues (ATOM records):
    >7kraM (M:)
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  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records:
    >7kraN (N:)
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