PDB entry 7kr4

View 7kr4 on RCSB PDB site
Description: human dna ligase 1(e346a/e592a) bound to a nicked dna substrate control duplex
Deposited on 2020-11-18, released 2021-02-03
The last revision was dated 2021-02-03, with a file datestamp of 2021-01-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA ligase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LIG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18858 (4-End)
      • expression tag (0-3)
      • engineered mutation (88)
      • engineered mutation (334)
  • Chain 'B':
    Compound: DNA (5'-d(*ap*ap*tp*gp*tp*cp*tp*gp*cp*cp*c)-3')
    Species: SACCHAROMYCES CEREVISIAE, synthetic [TaxId:4932]
  • Chain 'C':
    Compound: DNA (5'-d(p*ap*tp*tp*cp*tp*gp*c)-3')
    Species: SACCHAROMYCES CEREVISIAE, synthetic [TaxId:4932]
  • Chain 'D':
    Compound: DNA (5'-d(*gp*cp*ap*gp*ap*ap*tp*gp*gp*gp*cp*ap*gp*ap*cp*ap*tp*t)-3')
    Species: SACCHAROMYCES CEREVISIAE, synthetic [TaxId:4932]
  • Heterogens: AMP, ACT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kr4A (A:)
sndmdpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsarlrmvetlsnllr
svvalsppdllpvlylslnhlgppqqglalgvgdgvllkavaqatgrqlesvraeaaekg
dvglvaensrstqrlmlppppltasgvfskfrdiarltgsastakkidiikglfvacrhs
earfiarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwle
eqgmilkqtfcevpdldriipvllehglerlpehcklspgiplkpmlahptrgisevlkr
feeaaftceykydgqraqihaleggevkifsrnqadntgkypdiisripkiklpsvtsfi
ldteavawdrekkqiqpfqvlttrkrkevdaseiqvqvclyafdliylngeslvreplsr
rrqllrenfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiak
rshnwlklkkdyldgvgdtldlvvigaylgrgkragryggfllasydedseelqaicklg
tgfsdeeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypa
arglvdsdkgislrfprfirvredkqpeqattsaqvaclyrkqsqiq

    Sequence, based on observed residues (ATOM records):
    >7kr4A (A:)
sndmdpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsarlrmvetlsnllr
svvalsppdllpvlylslnhlgppqqglalgvgdgvllkavaqatgrqlesvraeaaekg
dvglvaensrstppppltasgvfskfrdiarltgsastakkidiikglfvacrhsearfi
arslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqgmi
lkqtfcevpdldriipvllehglerlpehcklspgiplkpmlahptrgisevlkrfeeaa
ftceykydgqraqihaleggevkifsrnqadntgkypdiisripkiklpsvtsfildtea
vawdrekkqiqpfqvlttrkrkevdaseiqvqvclyafdliylngeslvreplsrrrqll
renfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiakrshnw
lklkkdyldgvgdtldlvvigaylgrgkragryggfllasydedseelqaicklgtgfsd
eeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypaarglv
dsdkgislrfprfirvredkqpeqattsaqvaclyrkqs

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.