PDB entry 7kqy

View 7kqy on RCSB PDB site
Description: crystal structure and characterization of human heavy-chain only antibodies reveals a novel, stable dimeric structure similar to monoclonal antibodies
Deposited on 2020-11-18, released 2020-12-16
The last revision was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: XRAY
Resolution: 2.91 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heavy-Chain only Human Antibodies
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KQY (0-End)
  • Chain 'B':
    Compound: Heavy-Chain only Human Antibodies
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KQY
  • Chain 'C':
    Compound: Heavy-Chain only Human Antibodies
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KQY
  • Chain 'D':
    Compound: Heavy-Chain only Human Antibodies
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KQY (0-End)
  • Chain 'E':
    Compound: Heavy-Chain only Human Antibodies
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KQY (0-End)
  • Chain 'F':
    Compound: Heavy-Chain only Human Antibodies
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KQY (0-End)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kqyA (A:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthtevqlvqsgaevkkpga
svkvscktsgytftnyginwvrqapgqglewigyiyigagdtdysekfkgratitsdtsa
stvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgpsvfplapsskstsg
gtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqt
yicnvnhkpsntkvdkkvepkscdktht

    Sequence, based on observed residues (ATOM records):
    >7kqyA (A:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapssksgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7kqyB (B:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthtevqlvqsgaevkkpga
svkvscktsgytftnyginwvrqapgqglewigyiyigagdtdysekfkgratitsdtsa
stvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgpsvfplapsskstsg
gtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqt
yicnvnhkpsntkvdkkvepkscdktht

    Sequence, based on observed residues (ATOM records):
    >7kqyB (B:)
vqlvqsgaevkkpgasvkvscktstftnyginwvrqapgqglewigyiyigagdtdysek
fkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgps
vplaptaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpsssl
gtqtyicnvnhkpsntkvdkkve

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7kqyC (C:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthtevqlvqsgaevkkpga
svkvscktsgytftnyginwvrqapgqglewigyiyigagdtdysekfkgratitsdtsa
stvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgpsvfplapsskstsg
gtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqt
yicnvnhkpsntkvdkkvepkscdktht

    Sequence, based on observed residues (ATOM records):
    >7kqyC (C:)
vqlvqsgaevkkpgasvkvscktstftnyginwvrqapgqglewigyiyigagdtdysek
fkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgps
vfplaptaalgclvkdyfpepvtvswnsgaltsgvhtfpavsglyslssvvtvpssslgt
qtyicnvnhkpsntkvdkkvep

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7kqyD (D:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthtevqlvqsgaevkkpga
svkvscktsgytftnyginwvrqapgqglewigyiyigagdtdysekfkgratitsdtsa
stvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgpsvfplapsskstsg
gtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqt
yicnvnhkpsntkvdkkvepkscdktht

    Sequence, based on observed residues (ATOM records):
    >7kqyD (D:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtfvywgqgtlvtvssastkgps
vfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvps
sslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7kqyE (E:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthtevqlvqsgaevkkpga
svkvscktsgytftnyginwvrqapgqglewigyiyigagdtdysekfkgratitsdtsa
stvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgpsvfplapsskstsg
gtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqt
yicnvnhkpsntkvdkkvepkscdktht

    Sequence, based on observed residues (ATOM records):
    >7kqyE (E:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7kqyF (F:)
evqlvqsgaevkkpgasvkvscktsgytftnyginwvrqapgqglewigyiyigagdtdy
sekfkgratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthtevqlvqsgaevkkpga
svkvscktsgytftnyginwvrqapgqglewigyiyigagdtdysekfkgratitsdtsa
stvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgpsvfplapsskstsg
gtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqt
yicnvnhkpsntkvdkkvepkscdktht

    Sequence, based on observed residues (ATOM records):
    >7kqyF (F:)
evqlvqsgaevkkpgasvkvscktsgyginwvrqapgqglewigyiyigagdtdysekfk
gratitsdtsastvymelsslrsedtavyycagtgtrfvywgqgtlvtvssastkgpsvf
plapstaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpsssl
gtqtyicnvnhkpsntkvdkkvep