PDB entry 7kp4

View 7kp4 on RCSB PDB site
Description: crystal structure of human claudin-4 in complex with clostridium perfringens enterotoxin c-terminal domain
Deposited on 2020-11-10, released 2020-12-09
The last revision was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 3.37 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Claudin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: CLDN4, CPER, CPETR1, WBSCR8
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: heat-labile enterotoxin b chain
    Species: Clostridium perfringens [TaxId:1502]
    Gene: CPE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01558 (1-128)
      • initiating methionine (0)
      • expression tag (129-133)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kp4A (A:)
masmglqvmgialavlgwlavmlccalpmwrvtafigsnivtsqtiweglwmncvvqstg
qmqckvydsllalpqdlqaaralviisiivaalgvllsvvggkctncledesakaktmiv
agvvfllaglmvivpvswtahniiqdfynplvasgqkremgaslyvgwaasgllllgggl
lccncpprtdkpysakysaarsaaasnyvglvpr

    Sequence, based on observed residues (ATOM records):
    >7kp4A (A:)
glqvmgialavlgwlavmlccalpmwrvtafigsnivtsqtiweglwmncvvqstgqmqc
kvydsllalpqdlqaaralviisiivaalgvllsvvggkctncledesakaktmivagvv
fllaglmvivpvswtahniiqdfynplvasgqkremgaslyvgwaasgllllgggllccn
cp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >7kp4B (B:)
mstdiekeildlaaaterlnltdalnsnpagnlydwrssnsypwtqklnlhltitatgqk
yrilaskivdfniysnnfnnlvkleqslgdgvkdhyvdisldagqyvlvmkanssysgny
pysilfqkfglvpr