PDB entry 7kmg

View 7kmg on RCSB PDB site
Description: LY-CoV555 neutralizing antibody against SARS-CoV-2
Class: immune system/viral protein
Keywords: antibody neutralizing SARS-CoV-2, IMMUNE SYSTEM, IMMUNE SYSTEM-VIRAL PROTEIN complex
Deposited on 2020-11-02, released 2021-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-27, with a file datestamp of 2021-01-22.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: LY-CoV555 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KMG (0-End)
    Domains in SCOPe 2.08: d7kmga1, d7kmga2
  • Chain 'B':
    Compound: LY-CoV555 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KMG (0-211)
    Domains in SCOPe 2.08: d7kmgb1, d7kmgb2
  • Chain 'C':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7kmgc_
  • Chain 'D':
    Compound: LY-CoV555 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KMG (0-End)
    Domains in SCOPe 2.08: d7kmgd1, d7kmgd2
  • Chain 'E':
    Compound: LY-CoV555 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7KMG (0-211)
    Domains in SCOPe 2.08: d7kmge1, d7kmge2
  • Chain 'F':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7kmgf_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kmgA (A:)
qvqlvqsgaevkkpgssvkvsckasggtfsnyaiswvrqapgqglewmgriipilgiany
aqkfqgrvtitadkststaymelsslrsedtavyycargyyearhyyyyyamdvwgqgta
vtvssastkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrvhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7kmgA (A:)
qvqlvqsgaevkkpgssvkvsckasggtfsnyaiswvrqapgqglewmgriipilgiany
aqkfqgrvtitadkststaymelsslrsedtavyycargyyearhyyyyyamdvwgqgta
vtvssastkgpsvfplapcssestaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrvhhhhh

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7kmgB (B:)
diqmtqspsslsasvgdrvtitcrasqsissylswyqqkpgkapklliyaasslqsgvps
rfsgsgsgtdftltitslqpedfatyycqqsystprtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevtqgttsvtksfnrgec

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7kmgC (C:)
fpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkln
dlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggn
ynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpy
rvvvlsfellhapatvcgphhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7kmgC (C:)
nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcft
nvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyly
rlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvl
sfellhapatvcg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7kmgD (D:)
qvqlvqsgaevkkpgssvkvsckasggtfsnyaiswvrqapgqglewmgriipilgiany
aqkfqgrvtitadkststaymelsslrsedtavyycargyyearhyyyyyamdvwgqgta
vtvssastkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrvhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7kmgD (D:)
qvqlvqsgaevkkpgssvkvsckasggtfsnyaiswvrqapgqglewmgriipilgiany
aqkfqgrvtitadkststaymelsslrsedtavyycargyyearhyyyyyamdvwgqgta
vtvssastkgpsvfplapcssestaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrvhh

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7kmgE (E:)
diqmtqspsslsasvgdrvtitcrasqsissylswyqqkpgkapklliyaasslqsgvps
rfsgsgsgtdftltitslqpedfatyycqqsystprtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevtqgttsvtksfnrgec

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7kmgF (F:)
fpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkln
dlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggn
ynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpy
rvvvlsfellhapatvcgphhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7kmgF (F:)
cpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnv
yadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrl
frksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvlsf
ellhapatvcg