PDB entry 7kjw

View 7kjw on RCSB PDB site
Description: structure of hiv-1 reverse transcriptase initiation complex core with efavirenz
Deposited on 2020-10-26, released 2021-03-17
The last revision was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: EM
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse transcriptase/ribonuclease H
    Species: Human immunodeficiency virus type 1 group M subtype B (isolate BH10) [TaxId:11678]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366
      • engineered mutation (259)
      • conflict (281)
      • engineered mutation (479)
  • Chain 'B':
    Compound: Reverse transcriptase P51 SUBUNIT
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366
      • engineered mutation (281)
  • Chain 'C':
    Compound: HIV-1 viral RNA fragment
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
  • Chain 'D':
    Compound: tRNA lysine 3 fragment with GNRA tetraloop
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: EFZ, MG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kjwA (A:)
mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpynt
pvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsv
pldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdi
viyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdk
wtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkaltevipltee
aelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmr
gahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvn
tpplvklwyqlekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktq
lqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpa
hkgiggneqvdklvsagirkil

    Sequence, based on observed residues (ATOM records):
    >7kjwA (A:)
pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfai
kwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyvgsdlei
gqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvn
dicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvh
gvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqki
ttesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepiv
gaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktqlqaiylalqdsglevni
vtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsag
irk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7kjwB (B:)
mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpynt
pvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsv
pldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdi
viyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdk
wtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkaltevipltee
aelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmr
gahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvn
tpplvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records):
    >7kjwB (B:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttgyelhpdkwtvqpivlpekdswtvndiq
klvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvy
ydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmtndvkqlteavqkittesivi
wgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.