PDB entry 7kfn

View 7kfn on RCSB PDB site
Description: structure of human adenosine deaminase acting on dsrna (adar2) bound to dsrna containing a 2'-deoxy benner's base z opposite the edited base
Deposited on 2020-10-14, released 2021-06-16
The last revision was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Double-stranded RNA-specific editase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ADARB1, ADAR2, DRADA2, RED1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Gli1 8AZ 23mer RNA
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'C':
    Compound: Gli1 1W5 23mer RNA
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'D':
    Compound: Double-stranded RNA-specific editase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ADARB1, ADAR2, DRADA2, RED1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 1W5, 8AZ, IHP, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kfnA (A:)
lhldqtpsrqpipseglqlhlpqvladavsrlvlgkfgdltdnfsspharrkvlagvvmt
tgtdvkdakvisvstgtkcingeymsdrglalndchaeiisrrsllrflytqlelylnnk
ddqkrsifqkserggfrlkenvqfhlyistspcgdarifsphepileepadrhpnrkarg
qlrtkiesgegtipvrsnasiqtwdgvlqgerlltmscsdkiarwnvvgiqgsllsifve
piyfssiilgslyhgdhlsramyqrisniedlpplytlnkpllsgisnaearqpgkapnf
svnwtvgdsaievinattgkdelgrasrlckhalycrwmrvhgkvpshllrskitkpnvy
hesklaakeyqaakarlftafikaglgawvekpteqdqfsltp

    Sequence, based on observed residues (ATOM records):
    >7kfnA (A:)
lhlpqvladavsrlvlgkfgdltdnfsspharrkvlagvvmttgtdvkdakvisvstgtk
cingeymsdrglalndchaeiisrrsllrflytqlelylnnkddqkrsifqkserggfrl
kenvqfhlyistspcgdarifsphepileepadrhpnrkargqlrtkiesgegtipvrsn
asiqtwdgvlqgerlltmscsdkiarwnvvgiqgsllsifvepiyfssiilgslyhgdhl
sramyqrisniedlpplytlnkpllsgisnaearqpgkapnfsvnwtvgdsaievinatt
gkdelgrasrlckhalycrwmrvhgkvpshllrskitkpnvyhesklaakeyqaakarlf
tafikaglgawvekpteqdqfslt

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7kfnD (D:)
lhldqtpsrqpipseglqlhlpqvladavsrlvlgkfgdltdnfsspharrkvlagvvmt
tgtdvkdakvisvstgtkcingeymsdrglalndchaeiisrrsllrflytqlelylnnk
ddqkrsifqkserggfrlkenvqfhlyistspcgdarifsphepileepadrhpnrkarg
qlrtkiesgegtipvrsnasiqtwdgvlqgerlltmscsdkiarwnvvgiqgsllsifve
piyfssiilgslyhgdhlsramyqrisniedlpplytlnkpllsgisnaearqpgkapnf
svnwtvgdsaievinattgkdelgrasrlckhalycrwmrvhgkvpshllrskitkpnvy
hesklaakeyqaakarlftafikaglgawvekpteqdqfsltp

    Sequence, based on observed residues (ATOM records):
    >7kfnD (D:)
hlpqvladavsrlvlgkfgdltdnfsspharrkvlagvvmttgtdvkdakvisvstgtkc
ingeymsdrglalndchaeiisrrsllrflytqlelylnnkddqkrsifqkserggfrlk
envqfhlyistspcgdarifsphepargqlrtkiesgegtipvrrlltmscsdkiarwnv
vgiqgsllsifvepiyfssiilgslyhgdhlsramyqrisniedlpplytlnkpllsgis
naearqpgkapnfsvnwtvgdsaievinattgkdelgrasrlckhalycrwmrvhgkvps
hllrskitkpnvyhesklaakeyqaakarlftafikaglgawvekpteqdqfslt