PDB entry 7kep

View 7kep on RCSB PDB site
Description: avibactam-CDD-1 2 minute complex
Class: hydrolase/inhibitor
Keywords: antibiotic resistance, mutant, Gram-positive, inhibitor, HYDROLASE, HYDROLASE-INHIBITOR complex
Deposited on 2020-10-11, released 2021-01-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-26, with a file datestamp of 2021-05-21.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Clostridioides difficile [TaxId:1496]
    Gene: blaR1_4, blaR1_1, E5F39_11445, SAMEA2239407_03320, SAMEA3374989_01677
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A160YKM3
      • engineered mutation (237)
      • engineered mutation (243)
    Domains in SCOPe 2.08: d7kepa_
  • Heterogens: NXL, FYG, SO4, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kepA (A:)
mkrkknfiwiaillvgvvmvmyyavkkhndinqktdknyikselnkskiknndknkkesv
nivdysdcfegisggaifcntknkeyniynkelietrrspcstfkivstliglekgvins
kesvmgydgtdypnknwnknlsleeafkescvwyykklinkvdaksvqnilddlkygncd
isewegdlkngkghlngfwlesslqispkeqvqtmakifegdtnfkkehinilrdimaid
vndaninvygktgtgfdeknkrvdawfvgmleregdtyyfaiksddsnkeitgpkvkeia
iniikkyysvre

    Sequence, based on observed residues (ATOM records): (download) 
    >7kepA (A:)
svnivdysdcfegisggaifcntknkeyniynkelietrrspcstfkivstliglekgvi
nskesvmgydgtdypnknwnknlsleeafkescvwyykklinkvdaksvqnilddlkygn
cdisewegdlkngkghlngfwlesslqispkeqvqtmakifegdtnfkkehinilrdima
idvndaninvygktgtgfdeknkrvdawfvgmleregdtyyfaiksddsnkeitgpkvke
iainiikkyys