PDB entry 7kct

View 7kct on RCSB PDB site
Description: Crystal Structure of the Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase (OGC) Biotin Carboxylase (BC) Domain Dimer in Complex with Adenosine 5'-Diphosphate Magnesium Salt (MgADP), Adenosine 5'-Diphosphate (ADP, and Bicarbonate Anion (Hydrogen Carbonate/HCO3-)
Class: ligase
Keywords: biotin carboxylase, biotin-dependent carboxylase, pyruvate carboxylase, ATP-grasp, Aquificales, rTCA, dimer interface, bicarbonate, Sequence Determining Positions, structural waters, thermophile, carbon fixation, thermophilic protein, dimer, wet interface, LIGASE
Deposited on 2020-10-07, released 2021-01-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-oxoglutarate carboxylase small subunit
    Species: Hydrogenobacter thermophilus [TaxId:940]
    Gene: cfiB, HTH_1393, Hydth_1383
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3DJ42 (9-End)
      • expression tag (7-8)
    Domains in SCOPe 2.07: d7kcta1, d7kcta2, d7kcta3, d7kcta4
  • Chain 'B':
    Compound: 2-oxoglutarate carboxylase small subunit
    Species: Hydrogenobacter thermophilus [TaxId:940]
    Gene: cfiB, HTH_1393, Hydth_1383
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3DJ42 (9-End)
      • expression tag (7-8)
    Domains in SCOPe 2.07: d7kctb1, d7kctb2, d7kctb3, d7kctb4
  • Heterogens: ADP, BCT, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kctA (A:)
mkhhhhhhqmfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmadeaymi
gvnpldtylnaerivdlalevgaeaihpgygflaenehfarlceekgitfigphwkviel
mgdkarskevmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgiricr
neeelvrnyenayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerdcsiq
rrnqklveiapsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfiemntr
iqvehpvtemitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgfapsi
gtieryyvpggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsaletyei
sgvkttipllinimkdkdfrdgkfttryleehphvfdyaehrdkedfvafisaviasyhg
l

    Sequence, based on observed residues (ATOM records): (download) 
    >7kctA (A:)
hqmfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmadeaymigvnpldt
ylnaerivdlalevgaeaihpgygflaenehfarlceekgitfigphwkvielmgdkars
kevmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgiricrneeelvr
nyenayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerdcsiqrrnqklv
eiapsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfiemntriqvehpv
temitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgfapsigtieryy
vpggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsaletyeisgvktti
pllinimkdkdfrdgkfttryleehphvfdyae

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7kctB (B:)
mkhhhhhhqmfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmadeaymi
gvnpldtylnaerivdlalevgaeaihpgygflaenehfarlceekgitfigphwkviel
mgdkarskevmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgiricr
neeelvrnyenayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerdcsiq
rrnqklveiapsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfiemntr
iqvehpvtemitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgfapsi
gtieryyvpggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsaletyei
sgvkttipllinimkdkdfrdgkfttryleehphvfdyaehrdkedfvafisaviasyhg
l

    Sequence, based on observed residues (ATOM records): (download) 
    >7kctB (B:)
hqmfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmadeaymigvnpldt
ylnaerivdlalevgaeaihpgygflaenehfarlceekgitfigphwkvielmgdkars
kevmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgiricrneeelvr
nyenayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerdcsiqrrnqklv
eiapsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfiemntriqvehpv
temitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgfapsigtieryy
vpggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsaletyeisgvktti
pllinimkdkdfrdgkfttryleehphvfdyae