PDB entry 7kal

View 7kal on RCSB PDB site
Description: cryo-em structure of the sec complex from t. lanuginosus, wild-type, class with sec62, plug-open conformation
Deposited on 2020-10-01, released 2021-01-06
The last revision was dated 2021-02-24, with a file datestamp of 2021-02-19.
Experiment type: EM
Resolution: 4 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein transport channel Sec61 complex, alpha subunit (Sec61)
    Species: THERMOMYCES LANUGINOSUS [TaxId:5541]
    Gene: Sec61a
    Database cross-references and differences (RAF-indexed):
    • PDB 7KAL
  • Chain 'B':
    Compound: Protein transport channel Sec61 complex, beta subunit (Sbh1)
    Species: THERMOMYCES LANUGINOSUS [TaxId:5541]
    Gene: Sec61b
    Database cross-references and differences (RAF-indexed):
    • PDB 7KAL
  • Chain 'C':
    Compound: Protein transport channel Sec61 complex, gamma subunit (Sss1)
    Species: THERMOMYCES LANUGINOSUS [TaxId:5541]
    Gene: Sec61G
    Database cross-references and differences (RAF-indexed):
    • PDB 7KAL
  • Chain 'D':
    Compound: Protein transport protein Sec63
    Species: THERMOMYCES LANUGINOSUS [TaxId:5541]
    Gene: Sec63
    Database cross-references and differences (RAF-indexed):
    • PDB 7KAL
  • Chain 'E':
    Compound: Protein transport protein Sec66/Sec71
    Species: THERMOMYCES LANUGINOSUS [TaxId:5541]
    Gene: SEC66
    Database cross-references and differences (RAF-indexed):
    • PDB 7KAL
  • Chain 'F':
    Compound: Protein transport protein Sec72
    Species: THERMOMYCES LANUGINOSUS [TaxId:5541]
    Gene: Sec72
    Database cross-references and differences (RAF-indexed):
    • PDB 7KAL
  • Chain 'G':
    Compound: Protein transport protein Sec62
    Species: THERMOMYCES LANUGINOSUS [TaxId:5541]
    Gene: SEC62
    Database cross-references and differences (RAF-indexed):
    • PDB 7KAL

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7kalA (A:)
msglrfldlikpftpllpevaapetkvpfnqklmwtgltlliflvmsqmplygivssdts
dplywlrmmlasnrgtlmelgitpiissgmvfqllagthlidvnldlktdrelyqtaqkl
faiilsfgqacvhvltglygqpsdlgagicvllivqlvvaglvvilldellqkgyglgsg
islfiatnicesivwkafspttintgrgpefegaiialfhllltwpdkqralreafyrqs
lpnimnllatllvfaaviylqgfrveipvksarqrgvrgsypvrlfytsnmpimlqsalc
snvflisqmlysrfsdnllvrllgvwepregsaqlhaasgiayymspplnfkealldpvh
tvvyitfmlvacalfsktwievsgssprdvakqlkdqglvmaghreqsmykelkrvipta
aafggacigalsvasdllgalgsgtgillavtiiygyfemaaregdfgqglrglvpgngs

    Sequence, based on observed residues (ATOM records):
    >7kalA (A:)
likpftpllpevaapetkvpfnqklmwtgltlliflvmsqmplygivssdasnrgtlmel
gitpiissgmvfqllagthvnldlktdrelyqtaqklfaiilsfgqacvhvltglygqps
dlgagicvllivqlvvaglvvilldellqkgyglgsgislfiatnicesivwkafsptti
ntgrgpefegaiialfhllltwpdkqralreafyrqslpnimnllatllvfaaviylqgf
rveipvksarqrgvrgsypvrlfytsnmpimlqsalcsnvflisqmlysrfsdnllvrll
gvweplhaasgiayymspplnfkealldpvhtvvyitfmlvacalfsktwievsgssprd
vakqlkdqglvmaghreqsmykelkrviptaaafggacigalsvasdllgalgsgtgill
avtiiygyfemaaregd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7kalB (B:)
massgaesgseskspnpgagsgpgsasgssagvirpssptppggpraairrraaadhkes
lrnarpsstraagaggssgtmlklytdespglrvdpvvvlvlslcfifsvvglhviakit
rkfss

    Sequence, based on observed residues (ATOM records):
    >7kalB (B:)
lrvdpvvvlvlslcfifsvvglhviakitrkf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7kalC (C:)
mseqvqelldiprdflkdgmqfihkcqkpdrkefkkvcqavaigfvamgaigyivklvhi
pinnilvags

    Sequence, based on observed residues (ATOM records):
    >7kalC (C:)
prdflkdgmqfihkcqkpdrkefkkvcqavaigfvamgaigyivklvhipinnilva

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7kalD (D:)
ggsggsggsggsggsmssreynydengqffpffvltltglvtlpltysllkppkkvesta
priksdfkpqhddiiqnqkrkrlrkerrvkraiavvvgwaiigymvyliivtrrtapkiw
dpyeilgisrsaderaiarrykrlsllyhpdkvrpdpsknetmemlnqrfveltkaykal
tdeeirnnylqyghpdgkqsysigialpkliieegsgkyvlmlyasllgillpyivgrww
ygsqrytrekvlaasagnmfreyegtmiggpivnalstgeeykemlsgpkaeeglakvek
kvlaldekilsakdrevlrkidnpvrrkalallwaylnridledpvlneekyeagsials
ltesftaialafgnlipiigayrisqcivqaispgsspllqlpyftpkvvesvegadvkt
hlsvqkyldmpeerrrsltvgpglltedqynsaiavakqlplfaiskaffkvagervvtp
sslvqlvikgriippgstgvpdvtekdledidpdeadvnaiigrkgatkpsgksgdendg
drvqpplahapylprdhpprwhifladakqgkiavppftfttfdkpifdeqgkptfnmqt
lrmqfqappqvgnfsfvlhmisdsymgfdvkqeitlqvedpskaavlqeeddisepdeds
iagqmqalktgvppkkkkvvesdddesdtegdeedtsetdtetdtdeegsgtgenlyfq

    Sequence, based on observed residues (ATOM records):
    >7kalD (D:)
ynydengqffpffvltltglvtlpltysllapriksdfkpqhddiiqnqkrkrlrkerrv
kraiavvvgwaiigymvyliivtrrtagsysigialpkliieegsgkyvlmlyasllgil
lpyivgrwwygsqrytrekvlaasagnmfreyegtmiggpivnalstgeeykemlsgpka
eeglakvekkvlaldekilsakdrevlrkidnpvrrkalallwaylnridledpvlneek
yeagsialsltesftaialafgnlipiigayrisqcivqaispgsspllqlpyftpkvve
svegadvkthlsvqkyldmpeerrrsltvgpglltedqynsaiavakqlplfaiskaffk
vagervvtpsslvqlvikgriippgrvqpplahapylprdhpprwhifladakqgkiavp
pftfttfdktfnmqtlrmqfqappqvgnfsfvlhmisdsymgfdvkqeitlqved

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7kalE (E:)
mdwltlvvpfaylgvligclatfsslyrrrkaakaaslepwfpphlqrdiyhsllhldqq
qqnekktrvpetvlkaallrraaedikrvmaireqkqalalllqrgsvgdelwqrflrae
kemedevrdvvaeansyapnwgqvifqsaremdanatyrarmeeyqatvaeerawwdkkr
asiqegfmkeldaekerpataastatnttsttsdddavlveaekegtsspapgkkkkkgk
kgs

    Sequence, based on observed residues (ATOM records):
    >7kalE (E:)
wltlvvpfaylgvligclatfsslyrrrkaakaaslepwfpphlqrdiyhsllhldqqqr
vpetvlkaallrraaedikrvmaireqkqalalllqrgsvgdelwqrflraekemedevr
dvvaeansyapnwgqvifqsaremdanatyrarmeeyqatvaeerawwdkkr

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7kalF (F:)
mssdldtythyplhldpsskavslattegqtpaqteaveaelqqlnalhrslisldppnv
pppplpinpkrsaqitklketantaykrgnhgeavrlysyaiemaagrpgwepvnlaree
lsglyanraqahmaqqmwpegwvdakcsveskpvgnakgwwrggkclvemgrydearawi
eqalgiegpasdggkelaalleeikagsqrrqgs

    Sequence, based on observed residues (ATOM records):
    >7kalF (F:)
tythyplhldpsskavslattgqtpaqteaveaelqqlnalhrslisldppnvpppplpi
npkrsaqitklketantaykrgnhgeavrlysyaiemaagrpgwepvnlareelsglyan
raqahmaqqmwpegwvdakcsveskpvgnakgwwrggkclvemgrydearawieqalgie
sdggkelaalleei

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7kalG (G:)
maapppgmtpqqfaalqqhmqqqiaaeaakrgmtveefskmqreqlnaeaakagmtpeqy
inqlrmralqqraamqqqmqqqqqqggqgqtqgqgqgqgqqgqgqpqvqhvqhvqqqvsv
npnappnpkaialakwlrsqnlkartcildgqrremfkvkralralespeyqkaaaknkl
lppvtdrasaenafkllplsflalrvskvssnynkgkrvkglwtvkveqhqdtdpmthyv
wlyegpqwkqkalaaafvigifaivlfplwpimlrqgvwylsvgmlgllglffalaivrl
ilfcvtvfvvppgiwlfpnlfedvgfidsfkplwawnekkkkpkkakaavsksqekgaap
ttaapeaptatttsseaqpssssgtaskrnlaasvedaeegs

    Sequence, based on observed residues (ATOM records):
    >7kalG (G:)
egpqwkqkalaaafvigifaivlfplwpimlrqgvwylsvgmlgllglffalaivrlilf
cv