PDB entry 7k8v

View 7k8v on RCSB PDB site
Description: structure of the sars-cov-2 s 2p trimer in complex with the human neutralizing antibody fab fragment, c110
Deposited on 2020-09-27, released 2020-10-21
The last revision was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: EM
Resolution: 3.8 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • conflict (606)
      • conflict (985-986)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • conflict (606)
      • conflict (985-986)
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • conflict (606)
      • conflict (985-986)
  • Chain 'H':
    Compound: C110 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K8V (0-End)
  • Chain 'L':
    Compound: C110 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K8V
  • Chain 'M':
    Compound: C110 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K8V (0-End)
  • Chain 'N':
    Compound: C110 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K8V
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7k8vA (A:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnevavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpsgrlvprgspgsgyipeaprdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7k8vA (A:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihpvlpfndgvyfasteks
niirgwifgttldsksllivnnatnvvikvcefqfcndpflgvctfeyvsfknlrefvfk
nidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllaayyvgylqprtf
llkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnl
cpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnv
yadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldnynylyrlfrksn
lkpferdisteiyqagegfncyfplqsygfqptnvgyqpyrvvvlsfellhapatvcgpk
kstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleildit
pcsfggvsvitpgtntsnevavlyqdvnctevnvfqtragcligaehvnnsyecdipiga
gicasyqtqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmy
icgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfn
fsqilpdpskskrsfiedllfnkvtfngltvlpplltdemiaqytsallagtitsgwtfg
agaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklq
dvvnqnaqalntlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvt
qqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvp
aqeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvv
igivnntvydplqpelds

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7k8vB (B:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnevavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpsgrlvprgspgsgyipeaprdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7k8vB (B:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhnpvlpfndgvyfasteksni
irgwifgttldsktqsllivnnatnvvikvcefqfcndpfnnctfeyvsfknlrefvfkn
yfkiyskhtpindlpqgfsaleplvdlpiginitrfqtllaayyvgylqprtfllkynen
gtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevf
natrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvi
rgdevrqiapgqtgkiadynyklpddftgcviawnsnnldnynylyrlfrksnlkpferd
isteiyqagegfncyfplqsygfqptnvgyqpyrvvvlsfellhapatvcgpkkstnlvk
nkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggv
svitpgtntsnevavlyqdvnctevnvfqtragcligaehvnnsyecdipigagicasyq
tsqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdst
ecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilp
dpskskrsfiedllfnkvtkfngltvlpplltdemiaqytsallagtitsgwtfgagaal
qipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq
naqalntlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqlir
aaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqekn
fttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivn
ntvydplqpelds

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7k8vC (C:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnevavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpsgrlvprgspgsgyipeaprdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7k8vC (C:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhnpvlpfndgvyfasteksni
irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvnctfeyvsfknlrefvf
knidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllayyvgylqprtf
llkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnl
cpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnv
yadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldnynylyrlfrksn
lkpferdisteiyqagegfncyfplqsygfqptnvgyqpyrvvvlsfellhapatvcgpk
kstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleildit
pcsfggvsvitpgtntsnevavlyqdvnctevnvfqtragcligaehvnnsyecdipiga
gicasyqtqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmy
icgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfn
fsqilpdpskskrsfiedllfnkvtngltvlpplltdemiaqytsallagtitsgwtfga
gaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqd
vvnqnaqalntlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtq
qliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpa
qeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvi
givnntvydplqpelds

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7k8vH (H:)
qvqlqqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiiypgdsdtry
spsfqgqvtisadksistaymqwsslkasdtamyycarsfrddpriavagpadafdiwgq
gtmvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records):
    >7k8vH (H:)
qvqlqqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiiypgdsdtry
spsfqgqvtisadksistaymqwsslkasdtamyycarsfrddpriavagpadafdiwgq
gtmvtv

  • Chain 'L':
    Sequence, based on SEQRES records:
    >7k8vL (L:)
diqmtqspstlsasvgdrvtitcrasqsisywlawyqqkpgkapklliyqasslesgvps
rfsgsesgteftltisslqpddfatyycqqynsypytfgqgtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >7k8vL (L:)
iqmtqspstlsasvgdrvtitcrasqsisywlawyqqkpgkapklliyqasslesgvpsr
fsgsesgteftltisslqpddfatyycqqynsypytfgqgtklei

  • Chain 'M':
    Sequence, based on SEQRES records:
    >7k8vM (M:)
qvqlqqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiiypgdsdtry
spsfqgqvtisadksistaymqwsslkasdtamyycarsfrddpriavagpadafdiwgq
gtmvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records):
    >7k8vM (M:)
qvqlqqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiiypgdsdtry
spsfqgqvtisadksistaymqwsslkasdtamyycarsfrddpriavagpadafdiwgq
gtmvtv

  • Chain 'N':
    Sequence, based on SEQRES records:
    >7k8vN (N:)
diqmtqspstlsasvgdrvtitcrasqsisywlawyqqkpgkapklliyqasslesgvps
rfsgsesgteftltisslqpddfatyycqqynsypytfgqgtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >7k8vN (N:)
iqmtqspstlsasvgdrvtitcrasqsisywlawyqqkpgkapklliyqasslesgvpsr
fsgsesgteftltisslqpddfatyycqqynsypytfgqgtklei