PDB entry 7k8n

View 7k8n on RCSB PDB site
Description: Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102
Class: immune system
Keywords: Human Neutralizing Antibody, SARS-CoV-2, Receptor Binding Domain, COVID-19, IMMUNE SYSTEM
Deposited on 2020-09-27, released 2020-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: C102 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K8N (0-217)
    Domains in SCOPe 2.08: d7k8na_
  • Chain 'B':
    Compound: C102 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K8N (0-213)
    Domains in SCOPe 2.08: d7k8nb1, d7k8nb2
  • Heterogens: SO4, GOL, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k8nA (A:)
qvqlvesgggliqpggslrlscaasgfivssnymswvrqapgkglewvsviysggstfya
dsvkgrftisrdnskntlylqmnslraedtavyycardygdyyfdywgqgtlvtvssast
kgpsvfplapssksxxxxtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

    Sequence, based on observed residues (ATOM records): (download) 
    >7k8nA (A:)
qvqlvesgggliqpggslrlscaasgfivssnymswvrqapgkglewvsviysggstfya
dsvkgrftisrdnskntlylqmnslraedtavyycardygdyyfdywgqgtlvtvssast
kgpsvfplapsskstaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7k8nB (B:)
eivltqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgip
drfsgsgsgtdftltisrlepedfavyycqqygssprtfgqgtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrge