PDB entry 7k88

View 7k88 on RCSB PDB site
Description: Crystal structure of bovine RPE65 in complex with hexaethylene glycol monooctyl ether
Class: isomerase,hydrolase/inhibitor
Keywords: Non-heme iron, isomerohydrolase, C8E6, inhibitor, beta-propeller, ISOMERASE, HYDROLASE-INHIBITOR complex
Deposited on 2020-09-26, released 2021-06-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoid isomerohydrolase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q28175 (0-531)
      • conflict (339)
    Domains in SCOPe 2.07: d7k88a_
  • Chain 'B':
    Compound: Retinoid isomerohydrolase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q28175 (0-531)
      • conflict (339)
    Domains in SCOPe 2.07: d7k88b_
  • Heterogens: 32M, FE2, PG4, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k88A (A:)
ssqvehpaggykklfetveelsspltahvtgriplwltgsllrcgpglfevgsepfyhlf
dgqallhkfdfkeghvtyhrrfirtdayvramtekrivitefgtcafpdpcknifsrffs
yfrgvevtdnalvniypvgedyyactetnfitkvnpetletikqvdlcnyvsvngatahp
hiendgtvynigncfgknfsiaynivkipplqadkedpiskseivvqfpcsdrfkpsyvh
sfgltpnyivfvetpvkinlfkflsswslwganymdcfesnetmgvwlhiadkkrkkyin
nkyrtspfnlfhhintyedheflivdlccwkgfefvynylylanlrenweevkknarkap
qpevrryvlplnidkadtgknlvtlpnttatailcsdetiwlepevlfsgprqafefpqi
nyqkyggkpytyayglglnhfvpdrlcklnvktketwvwqepdsypsepifvshpdalee
ddgvvlsvvvspgagqkpayllilnakdlsevaraeveinipvtfhglfkks

    Sequence, based on observed residues (ATOM records): (download) 
    >7k88A (A:)
ssqvehpaggykklfetveelsspltahvtgriplwltgsllrcgpglfevgsepfyhlf
dgqallhkfdfkeghvtyhrrfirtdayvramtekrivitefgtcafevtdnalvniypv
gedyyactetnfitkvnpetletikqvdlcnyvsvngatahphiendgtvynigncfgsi
aynivkipplqadkedpiskseivvqfpcsdrfkpsyvhsfgltpnyivfvetpvkinlg
anymdcfesnetmgvwlhiadkkrkkyinnkyrtspfnlfhhintyedheflivdlccwk
gfefvynylylanlrenweevkknarkapqpevrryvlplnidkadtgknlvtlpnttat
ailcsdetiwlepevlfsgprqafefpqinyqkyggkpytyayglglnhfvpdrlcklnv
ktketwvwqepdsypsepifvshpdaleeddgvvlsvvvspgagqkpayllilnakdlse
varaeveinipvtfhglfkks

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7k88B (B:)
ssqvehpaggykklfetveelsspltahvtgriplwltgsllrcgpglfevgsepfyhlf
dgqallhkfdfkeghvtyhrrfirtdayvramtekrivitefgtcafpdpcknifsrffs
yfrgvevtdnalvniypvgedyyactetnfitkvnpetletikqvdlcnyvsvngatahp
hiendgtvynigncfgknfsiaynivkipplqadkedpiskseivvqfpcsdrfkpsyvh
sfgltpnyivfvetpvkinlfkflsswslwganymdcfesnetmgvwlhiadkkrkkyin
nkyrtspfnlfhhintyedheflivdlccwkgfefvynylylanlrenweevkknarkap
qpevrryvlplnidkadtgknlvtlpnttatailcsdetiwlepevlfsgprqafefpqi
nyqkyggkpytyayglglnhfvpdrlcklnvktketwvwqepdsypsepifvshpdalee
ddgvvlsvvvspgagqkpayllilnakdlsevaraeveinipvtfhglfkks

    Sequence, based on observed residues (ATOM records): (download) 
    >7k88B (B:)
ssqvehpaggykklfetveelsspltahvtgriplwltgsllrcgpglfevgsepfyhlf
dgqallhkfdfkeghvtyhrrfirtdayvramtekrivitefgtcafpgvevtdnalvni
ypvgedyyactetnfitkvnpetletikqvdlcnyvsvngatahphiendgtvynignci
aynivkipplqadkedpiskseivvqfpcsdrfkpsyvhsfgltpnyivfvetpvkinlf
kganymdcfesnetmgvwlhiadkkrkkyinnkyrtspfnlfhhintyedheflivdlcc
wkgfefvynylylanlrenweevkknarkapqpevrryvlplnidkadtgknlvtlpntt
atailcsdetiwlepevlfsgprqafefpqinyqkyggkpytyayglglnhfvpdrlckl
nvktketwvwqepdsypsepifvshpdaleeddgvvlsvvvspgagqkpayllilnakdl
sevaraeveinipvtfhglfkks