PDB entry 7k7y

View 7k7y on RCSB PDB site
Description: crystal structure of bont/e lc-hn domain in complex with vhh jle-e9
Deposited on 2020-09-24, released 2020-10-14
The last revision was dated 2020-10-14, with a file datestamp of 2020-10-09.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: botulinum neurotoxin type E
    Species: Clostridium botulinum [TaxId:1491]
    Gene: bont, FDB75_10755
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: botulinum neurotoxin type E
    Species: Clostridium botulinum [TaxId:1491]
    Gene: bont, FDB75_10755
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: jle-e9
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K7Y
  • Chain 'D':
    Compound: jle-e9
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K7Y
  • Chain 'E':
    Compound: botulinum neurotoxin type E
    Species: Clostridium botulinum [TaxId:1491]
    Gene: bont, FDB75_10755
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: jle-e9
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K7Y
  • Chain 'G':
    Compound: botulinum neurotoxin type E
    Species: Clostridium botulinum [TaxId:1491]
    Gene: bont, FDB75_10755
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: jle-e9
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K7Y

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7k7yA (A:)
gplgsmpkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdf
hpptslkngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylg
ndntpdnqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsn
hgfgsiaivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitq
kqnplitnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpl
lnpykdvfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqy
kyfklsnllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfckni
vsvkgirksicieinngelffvasensynddnintpkeiddtvtsnnnyendldqvilnf
nsesapglsdeklnltiqndayipkydsngtsdieqhdvnelnvffyldaqkvpegennv
nltssidtalleqpkiytffssefinnvnkpvqaalfvswiqqvlvdftteanqkstvdk
iadisivvpyiglalnigneaqkgnfkdalellgagillefepelliptilvftiksflg
ssdnknkvikainnalkerdekwkevysfivsnwmtkintqfnkrkeqmyqalqnqvnai
ktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfltessisylmklin
evkinklreydenvktyllnyiiqhgsilgesqqelnsmvtdtlnnsipfklssytddki
lisyfnkffk

    Sequence, based on observed residues (ATOM records):
    >7k7yA (A:)
mpkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhppts
lkngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntp
dnqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgs
iaivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpl
itnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpyk
dvfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkl
snllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkg
irksicieinngelffvasensynddnintpkeiddtvydsngtsdieqhdvnelnvffy
ldaqkvpegennvnltssidtalleqpkiytffssefinnvnkpvqaalfvswiqqvlvd
ftteanqkstvdkiadisivvpyiglalnigneaqkgnfkdalellgagillefepelli
ptilvftiksflgssdnknkvikainnalkerdekwkevysfivsnwmtkintqfnkrke
qmyqalqnqvnaiktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfl
tessisylmklinevkinklreydenvktyllnyiiqhgsilgesqqelnsmvtdtlnns
ipfklssyt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7k7yB (B:)
gplgsmpkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdf
hpptslkngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylg
ndntpdnqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsn
hgfgsiaivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitq
kqnplitnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpl
lnpykdvfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqy
kyfklsnllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfckni
vsvkgirksicieinngelffvasensynddnintpkeiddtvtsnnnyendldqvilnf
nsesapglsdeklnltiqndayipkydsngtsdieqhdvnelnvffyldaqkvpegennv
nltssidtalleqpkiytffssefinnvnkpvqaalfvswiqqvlvdftteanqkstvdk
iadisivvpyiglalnigneaqkgnfkdalellgagillefepelliptilvftiksflg
ssdnknkvikainnalkerdekwkevysfivsnwmtkintqfnkrkeqmyqalqnqvnai
ktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfltessisylmklin
evkinklreydenvktyllnyiiqhgsilgesqqelnsmvtdtlnnsipfklssytddki
lisyfnkffk

    Sequence, based on observed residues (ATOM records):
    >7k7yB (B:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpli
tnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykd
vfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkls
nllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkgi
rksicieinngelffvasensynddnintpkeiddtydsngtsdieqhdvnelnvffyld
aqkvpegennvnltssidtalleqpkiytffssefinnvnkpvqaalfvswiqqvlvdft
teanqkstvdkiadisivvpyiglalnigneaqkgnfkdalellgagillefepellipt
ilvftiksflnknkvikainnalkerdekwkevysfivsnwmtkintqfnkrkeqmyqal
qnqvnaiktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfltessis
ylmklinevkinklreydenvktyllnyiiqhgsilgesqqelnsmvtdtlnnsipfkls
syt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7k7yC (C:)
gplgsqlqlvetggglvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsng
dstfyadsikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywg
qgtqvtvss

    Sequence, based on observed residues (ATOM records):
    >7k7yC (C:)
qlqlvetggglvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsngdstfy
adsikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywgqgtqv
tvs

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7k7yD (D:)
gplgsqlqlvetggglvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsng
dstfyadsikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywg
qgtqvtvss

    Sequence, based on observed residues (ATOM records):
    >7k7yD (D:)
gsqlqlvetggglvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsngdst
fyadsikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywgqgt
qvtvs

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7k7yE (E:)
gplgsmpkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdf
hpptslkngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylg
ndntpdnqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsn
hgfgsiaivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitq
kqnplitnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpl
lnpykdvfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqy
kyfklsnllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfckni
vsvkgirksicieinngelffvasensynddnintpkeiddtvtsnnnyendldqvilnf
nsesapglsdeklnltiqndayipkydsngtsdieqhdvnelnvffyldaqkvpegennv
nltssidtalleqpkiytffssefinnvnkpvqaalfvswiqqvlvdftteanqkstvdk
iadisivvpyiglalnigneaqkgnfkdalellgagillefepelliptilvftiksflg
ssdnknkvikainnalkerdekwkevysfivsnwmtkintqfnkrkeqmyqalqnqvnai
ktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfltessisylmklin
evkinklreydenvktyllnyiiqhgsilgesqqelnsmvtdtlnnsipfklssytddki
lisyfnkffk

    Sequence, based on observed residues (ATOM records):
    >7k7yE (E:)
mpkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhppts
lkngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntp
dnqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgs
iaivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpl
itnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpyk
dvfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkl
snllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkg
irksicieinngelffvasensynddnintpkeiddtvydsngtsdieqhdvnelnvffy
ldaqkvpegennvnltssidtalleqpkiytffssefinnvnkpvqaalfvswiqqvlvd
ftteanqkstvdkiadisivvpyiglalnigneaqkgnfkdalellgagillefepelli
ptilvftikknkvikainnalkerdekwkevysfivsnwmtkintqfnkrkeqmyqalqn
qvnaiktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfltessisyl
mklinevkinklreydenvktyllnyiiqhsqqelnsmvtdtlnnsipfklssyt

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7k7yF (F:)
gplgsqlqlvetggglvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsng
dstfyadsikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywg
qgtqvtvss

    Sequence, based on observed residues (ATOM records):
    >7k7yF (F:)
qlqlvetggvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsngdstfyad
sikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywgqgtqv

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7k7yG (G:)
gplgsmpkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdf
hpptslkngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylg
ndntpdnqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsn
hgfgsiaivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitq
kqnplitnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpl
lnpykdvfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqy
kyfklsnllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfckni
vsvkgirksicieinngelffvasensynddnintpkeiddtvtsnnnyendldqvilnf
nsesapglsdeklnltiqndayipkydsngtsdieqhdvnelnvffyldaqkvpegennv
nltssidtalleqpkiytffssefinnvnkpvqaalfvswiqqvlvdftteanqkstvdk
iadisivvpyiglalnigneaqkgnfkdalellgagillefepelliptilvftiksflg
ssdnknkvikainnalkerdekwkevysfivsnwmtkintqfnkrkeqmyqalqnqvnai
ktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfltessisylmklin
evkinklreydenvktyllnyiiqhgsilgesqqelnsmvtdtlnnsipfklssytddki
lisyfnkffk

    Sequence, based on observed residues (ATOM records):
    >7k7yG (G:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfetnssnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpli
tnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykd
vfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkls
nllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkgi
rksicieinngelffvasensynddnintpkeiddtvdayipkydsntsdieqhdvneln
vffyldaqkvpegennvnltssidtalleqpkiytffssefinnvnkpvqaalfvswiqq
vlvdftteanqkstvdkiadisivvpyiglalnigneaqkgnfkdalellgagillefep
elliptilvftiksflnknkvikainnalkerdekwkevysfivsnwmtkintqfnkrke
qmyqalqnqvnaiktiieskynsytleekneltnkydikqienelnqkvsiamnnidrfl
tessisylmklinevkinklreydenvktyllnyiiqhgsilgesqqelnsmvtdtlnns
ipfklssyt

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7k7yH (H:)
gplgsqlqlvetggglvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsng
dstfyadsikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywg
qgtqvtvss

    Sequence, based on observed residues (ATOM records):
    >7k7yH (H:)
qlqlvetggglvqaggslrlscaasgrtfssysmgwfrqapgkereyvaavnsngdstfy
adsikgrftvsrdaakntvylqmnslkpedtalyycaavygrytyqspksyeywgqgtqv
tvs