PDB entry 7k6g
View 7k6g on RCSB PDB site
Description: Crystal structure of the first bromodomain (BD1) of human BRD4 bound to ERK5-IN-1
Class: gene regulation
Keywords: BET, ERK5, dual BRD-kinase inhibitor, GENE REGULATION
Deposited on
2020-09-20, released
2021-09-29
The last revision prior to the SCOPe 2.08 freeze date was dated
2021-11-24, with a file datestamp of
2021-11-19.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d7k6ga1, d7k6ga2 - Chain 'B':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d7k6gb1, d7k6gb2 - Heterogens: VYJ, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>7k6gA (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>7k6gB (B:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee