PDB entry 7k4w

View 7k4w on RCSB PDB site
Description: Crystal structure of Kemp Eliminase HG3.17 in the inactive state
Class: hydrolase
Keywords: kemp elimination, directed evolution, inactive state, HYDROLASE
Deposited on 2020-09-16, released 2020-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-30, with a file datestamp of 2020-12-25.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: endo-1,4-beta-xylanase
    Species: THERMOASCUS AURANTIACUS [TaxId:5087]
    Gene: xynA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23360
      • conflict (10)
      • conflict (41)
      • conflict (46)
      • conflict (48)
      • engineered mutation (51)
      • conflict (54)
      • conflict (85-88)
      • conflict (93-94)
      • conflict (109)
      • conflict (129)
      • conflict (134)
      • conflict (146)
      • conflict (176)
      • conflict (212)
      • conflict (238)
      • conflict (240-241)
      • conflict (271)
      • engineered mutation (304)
    Domains in SCOPe 2.08: d7k4wa_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k4wA (A:)
gsgmaeaaqsidqlikargkvyfgvatdqnrlttgknaaiikadfgmvwpeesmqwdate
psqgnfnfagadylvnwaqqngkligagclvwhnflpswvssitdkntlinvmknhittl
mtrykgkirtwdvvgeafnedgslrqnvflnvigedyipiafqtaraadpnaklyimdyn
ldsasypktqaivnrvkqwraagvpidgigsqmhlsagqgagvlqalpllasagtpevsi
lmldvagasptdyvnvvnaclnvqscvgitvmgvadpdsafasstpllfdgnfnpkpayn
aivqnlqq

    Sequence, based on observed residues (ATOM records): (download) 
    >7k4wA (A:)
aqsidqlikargkvyfgvatdqnrlttgknaaiikadfgmvwpeesmqwdatepsqgnfn
fagadylvnwaqqngkligagclvwhnflpswvssitdkntlinvmknhittlmtrykgk
irtwdvvgeafnedgslrqnvflnvigedyipiafqtaraadpnaklyimdynldsasyp
ktqaivnrvkqwraagvpidgigsqmhlsagqgagvlqalpllasagtpevsilmldvag
asptdyvnvvnaclnvqscvgitvmglfdgnfnpkpaynaivqnlq