PDB entry 7k3z

View 7k3z on RCSB PDB site
Description: p. falciparum cpn60 d474a mutant bound to atp
Deposited on 2020-09-14, released 2021-04-21
The last revision was dated 2021-04-21, with a file datestamp of 2021-04-16.
Experiment type: XRAY
Resolution: 3.69 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 60 kda chaperonin
    Species: Plasmodium falciparum (isolate 3D7) [TaxId:36329]
    Gene: PF3D7_1232100
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I0V3 (3-End)
      • engineered mutation (60)
      • engineered mutation (80)
      • engineered mutation (218)
      • engineered mutation (316)
      • engineered mutation (409)
  • Chain 'B':
    Compound: 60 kda chaperonin
    Species: Plasmodium falciparum (isolate 3D7) [TaxId:36329]
    Gene: PF3D7_1232100
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I0V3
      • engineered mutation (60)
      • engineered mutation (80)
      • engineered mutation (218)
      • engineered mutation (316)
      • engineered mutation (409)
  • Chain 'C':
    Compound: 60 kda chaperonin
    Species: Plasmodium falciparum (isolate 3D7) [TaxId:36329]
    Gene: PF3D7_1232100
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I0V3
      • engineered mutation (60)
      • engineered mutation (80)
      • engineered mutation (218)
      • engineered mutation (316)
      • engineered mutation (409)
  • Chain 'D':
    Compound: 60 kda chaperonin
    Species: Plasmodium falciparum (isolate 3D7) [TaxId:36329]
    Gene: PF3D7_1232100
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I0V3
      • engineered mutation (60)
      • engineered mutation (80)
      • engineered mutation (218)
      • engineered mutation (316)
      • engineered mutation (409)
  • Chain 'E':
    Compound: 60 kda chaperonin
    Species: Plasmodium falciparum (isolate 3D7) [TaxId:36329]
    Gene: PF3D7_1232100
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I0V3
      • engineered mutation (60)
      • engineered mutation (80)
      • engineered mutation (218)
      • engineered mutation (316)
      • engineered mutation (409)
  • Chain 'F':
    Compound: 60 kda chaperonin
    Species: Plasmodium falciparum (isolate 3D7) [TaxId:36329]
    Gene: PF3D7_1232100
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I0V3
      • engineered mutation (60)
      • engineered mutation (80)
      • engineered mutation (218)
      • engineered mutation (316)
      • engineered mutation (409)
  • Chain 'G':
    Compound: 60 kda chaperonin
    Species: Plasmodium falciparum (isolate 3D7) [TaxId:36329]
    Gene: PF3D7_1232100
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8I0V3
      • engineered mutation (60)
      • engineered mutation (80)
      • engineered mutation (218)
      • engineered mutation (316)
      • engineered mutation (409)
  • Heterogens: ATP, MG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7k3zA (A:)
mtgkgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiak
qislkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqr
giqlaskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiild
dnadindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpile
ifaknkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtns
kyisadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinv
lkkeyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaid
igyvpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmga
nivvssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstn
viisviknscsiasmvlttecmmvdhek

    Sequence, based on observed residues (ATOM records):
    >7k3zA (A:)
kgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiakqis
lkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqrgiq
laskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiilddna
dindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpileifa
knkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtnskyi
sadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinvlkk
eyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaidigy
vpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmganiv
vssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstnvii
sviknscsiasmvlttecmmvdhe

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7k3zB (B:)
mtgkgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiak
qislkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqr
giqlaskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiild
dnadindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpile
ifaknkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtns
kyisadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinv
lkkeyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaid
igyvpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmga
nivvssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstn
viisviknscsiasmvlttecmmvdhek

    Sequence, based on observed residues (ATOM records):
    >7k3zB (B:)
gkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiakqisl
kdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqrgiql
askmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiilddnad
indkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpileifak
nkqplciiaddfsnevlqtliinklkgaikvvpirapgdrrkdylkdlcivtnskyisad
vgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinvlkkeye
ettsydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaidigyvpgg
gvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmganivvssl
dvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstnviisvik
nscsiasmvlttecmmvdhe

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7k3zC (C:)
mtgkgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiak
qislkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqr
giqlaskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiild
dnadindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpile
ifaknkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtns
kyisadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinv
lkkeyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaid
igyvpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmga
nivvssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstn
viisviknscsiasmvlttecmmvdhek

    Sequence, based on observed residues (ATOM records):
    >7k3zC (C:)
gkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiakqisl
kdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqrgiql
askmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiilddnad
indkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpileifak
nkqplciiaddfsnevlqtliinklkgaikvvpirpsfgdrrkdylkdlcivtnskyisa
dvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinvlkkey
eettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaidigyvp
gggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmganivvs
sldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstnviisv
iknscsiasmvlttecmmvdhe

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7k3zD (D:)
mtgkgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiak
qislkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqr
giqlaskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiild
dnadindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpile
ifaknkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtns
kyisadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinv
lkkeyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaid
igyvpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmga
nivvssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstn
viisviknscsiasmvlttecmmvdhek

    Sequence, based on observed residues (ATOM records):
    >7k3zD (D:)
gkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiakqisl
kdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqrgiql
askmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiilddnad
indkleftegynfdrgiinpyllynendyieysqvstlitdqnidniqsilpileifakn
kqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtnskyisa
dvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinvlkkey
eettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaidigyvp
gggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmganivvs
sldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstnviisv
iknscsiasmvlttecmmvdhe

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7k3zE (E:)
mtgkgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiak
qislkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqr
giqlaskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiild
dnadindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpile
ifaknkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtns
kyisadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinv
lkkeyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaid
igyvpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmga
nivvssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstn
viisviknscsiasmvlttecmmvdhek

    Sequence, based on observed residues (ATOM records):
    >7k3zE (E:)
gkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiakqisl
kdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqrgiql
askmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiilddnad
indkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidiqsilpileifakn
kqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtnskyisa
dvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinvlkkey
eettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaidigyvp
gggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmganivvs
sldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstnviisv
iknscsiasmvlttecmmvdhe

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7k3zF (F:)
mtgkgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiak
qislkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqr
giqlaskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiild
dnadindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpile
ifaknkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtns
kyisadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinv
lkkeyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaid
igyvpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmga
nivvssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstn
viisviknscsiasmvlttecmmvdhek

    Sequence, based on observed residues (ATOM records):
    >7k3zF (F:)
gkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiakqisl
kdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqrgiql
askmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiilddnad
indkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpileifak
nkqplciiaddfsnevlqtliinklkgaikvvpirsfgdrrkdylkdlcivtnskyisad
vgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinvlkkeye
ettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaidigyvpg
ggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmganivvss
ldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstnviisvi
knscsiasmvlttecmmvdhe

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7k3zG (G:)
mtgkgkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiak
qislkdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqr
giqlaskmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiild
dnadindkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpile
ifaknkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtns
kyisadvgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinv
lkkeyeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaid
igyvpgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmga
nivvssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstn
viisviknscsiasmvlttecmmvdhek

    Sequence, based on observed residues (ATOM records):
    >7k3zG (G:)
gkdiiygnecrnellkgiltvsdvvkltlgprgrnvllekeygspliindgvtiakqisl
kdrkknngvklmqestqisndkagdgtsstalmtatitkkgieqvnrnhnpipiqrgiql
askmiiekikslstpiktykdilniatiasnndvhmgqiianaydklgknaaiilddnad
indkleftegynfdrgiinpyllynenkdyieysqvstlitdqnidniqsilpileifak
nkqplciiaddfsnevlqtliinklkgaikvvpirapsfgdrrkdylkdlcivtnskyis
advgldlnnlhnqmssfdnnylsllgsantlivkkdrtslitkeeykkeiderinvlkke
yeettskydkeklneriaalsggiakiliggnseteqkerkfkyeaatnavksaidigyv
pgggvtyleiiksnfiqeihkkieedlqissnndekkylelignlesemelqkmganivv
ssldvitkqiadnagvngdnvvkiilnskdkygfgydvntnkfvnmvekgiidstnviis
viknscsiasmvlttecmmvdhe