PDB entry 7k3q

View 7k3q on RCSB PDB site
Description: An ultra-potent human neutralizing antibody locks the SARS-CoV-2 spike in the closed conformation
Class: immune system
Keywords: SARS-CoV-2, neutralizing mAb, ANTIVIRAL PROTEIN, IMMUNE SYSTEM
Deposited on 2020-09-12, released 2020-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 1.38 Å
R-factor: N/A
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Fab fragment of S2E12 monoclonal antibody, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K3Q (0-225)
    Domains in SCOPe 2.08: d7k3qh_
  • Chain 'L':
    Compound: Fab fragment of S2E12 monoclonal antibody, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K3Q (0-215)
    Domains in SCOPe 2.08: d7k3ql1, d7k3ql2
  • Heterogens: GOL, EDO, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7k3qH (H:)
qvqlvqsgpevkkpgtsvrvsckasgftftssavqwvrqargqrlewvgwivvgsgntny
aqkfhervtitrdmststaymelsslrsedtavyycaspycsggscsdgfdiwgqgtmvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7k3qL (L:)
divltqtpgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgip
drfsgsgsgtdftltisrlepedfavyycqqyvgltgwtfgqgtkveikrtvaapsvfif
ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhkvyacevthqglsspvtksfnrgec