PDB entry 7k37

View 7k37 on RCSB PDB site
Description: Structure of full-length influenza HA with a head-binding antibody at pH 7.8
Class: viral protein
Keywords: influenza, virus, hemagglutinin, antibody, low pH, VIRAL PROTEIN
Deposited on 2020-09-10, released 2020-11-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-12-09, with a file datestamp of 2020-12-04.
Experiment type: EM
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Hong Kong/1/1968 H3N2) [TaxId:506350]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7k37a_
  • Chain 'B':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Hong Kong/1/1968 H3N2) [TaxId:506350]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7k37b_
  • Chain 'C':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Hong Kong/1/1968 H3N2) [TaxId:506350]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7k37c_
  • Chain 'D':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Hong Kong/1/1968 H3N2) [TaxId:506350]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7k37d_
  • Chain 'E':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Hong Kong/1/1968 H3N2) [TaxId:506350]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7k37e_
  • Chain 'F':
    Compound: Hemagglutinin
    Species: Influenza A virus (strain A/Hong Kong/1/1968 H3N2) [TaxId:506350]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7k37f_
  • Chain 'G':
    Compound: antibody fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K37
    Domains in SCOPe 2.07: d7k37g1, d7k37g2
  • Chain 'H':
    Compound: antibody fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K37 (0-End)
  • Chain 'I':
    Compound: antibody fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K37
    Domains in SCOPe 2.07: d7k37i1, d7k37i2
  • Chain 'J':
    Compound: antibody fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K37 (0-End)
  • Chain 'K':
    Compound: antibody fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K37
    Domains in SCOPe 2.07: d7k37k1, d7k37k2
  • Chain 'L':
    Compound: antibody fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K37 (0-End)
  • Heterogens: NAG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k37A (A:)
mktiialsyifclalgqdlpgndnstatlclghhavpngtlvktitddqievtnatelvq
ssstgkicnnphrildgidctlidallgdphcdvfqnetwdlfverskafsncypydvpd
yaslrslvassgtlefitegftwtgvtqnggsnackrgpgsgffsrlnwltksgstypvl
nvtmpnndnfdklyiwgvhhpstnqeqtslyvqasgrvtvstrrsqqtiipnigsrpwvr
glssrisiywtivkpgdvlvinsngnliaprgyfkmrtgkssimrsdapidtcisecitp
ngsipndkpfqnvnkitygacpkyvkqntlklatgmrnvpekqtr

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37A (A:)
statlclghhavpngtlvktitddqievtnatelvqssstgkicnnphrildgidctlid
allgdphcdvfqnetwdlfverskafsncypydvpdyaslrslvassgtlefitegftwt
gvtqnggsnackrgpgsgffsrlnwltksgstypvlnvtmpnndnfdklyiwgvhhpstn
qeqtslyvqasgrvtvstrrsqqtiipnigsrpwvrglssrisiywtivkpgdvlvinsn
gnliaprgyfkmrtgkssimrsdapidtcisecitpngsipndkpfqnvnkitygacpky
vkqntlklatgmrnvpek

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7k37B (B:)
glfgaiagfiengwegmidgwygfrhqnsegtgqaadlkstqaaidqingklnrviektn
ekfhqiekefsevegriqdlekyvedtkidlwsynaellvalenqhtidltdsemnklfe
ktrrqlrenaedmgngcfkiyhkcdnaciesirngtydhdvyrdealnnrfqikgvelks
gykdwilwisfaiscfllcvvllgfimwacqrgnircnicismgwshpqfekgggarggs
gggswshpqfekgf

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37B (B:)
glfgaiagfiengwegmidgwygfrhqnsegtgqaadlkstqaaidqingklnrviektn
ekfhqiekefsevegriqdlekyvedtkidlwsynaellvalenqhtidltdsemnklfe
ktrrqlrenaedmgngcfkiyhkcdnaciesirngtydhdvyrdealnnrfq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7k37C (C:)
mktiialsyifclalgqdlpgndnstatlclghhavpngtlvktitddqievtnatelvq
ssstgkicnnphrildgidctlidallgdphcdvfqnetwdlfverskafsncypydvpd
yaslrslvassgtlefitegftwtgvtqnggsnackrgpgsgffsrlnwltksgstypvl
nvtmpnndnfdklyiwgvhhpstnqeqtslyvqasgrvtvstrrsqqtiipnigsrpwvr
glssrisiywtivkpgdvlvinsngnliaprgyfkmrtgkssimrsdapidtcisecitp
ngsipndkpfqnvnkitygacpkyvkqntlklatgmrnvpekqtr

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37C (C:)
statlclghhavpngtlvktitddqievtnatelvqssstgkicnnphrildgidctlid
allgdphcdvfqnetwdlfverskafsncypydvpdyaslrslvassgtlefitegftwt
gvtqnggsnackrgpgsgffsrlnwltksgstypvlnvtmpnndnfdklyiwgvhhpstn
qeqtslyvqasgrvtvstrrsqqtiipnigsrpwvrglssrisiywtivkpgdvlvinsn
gnliaprgyfkmrtgkssimrsdapidtcisecitpngsipndkpfqnvnkitygacpky
vkqntlklatgmrnvpek

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7k37D (D:)
glfgaiagfiengwegmidgwygfrhqnsegtgqaadlkstqaaidqingklnrviektn
ekfhqiekefsevegriqdlekyvedtkidlwsynaellvalenqhtidltdsemnklfe
ktrrqlrenaedmgngcfkiyhkcdnaciesirngtydhdvyrdealnnrfqikgvelks
gykdwilwisfaiscfllcvvllgfimwacqrgnircnicismgwshpqfekgggarggs
gggswshpqfekgf

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37D (D:)
glfgaiagfiengwegmidgwygfrhqnsegtgqaadlkstqaaidqingklnrviektn
ekfhqiekefsevegriqdlekyvedtkidlwsynaellvalenqhtidltdsemnklfe
ktrrqlrenaedmgngcfkiyhkcdnaciesirngtydhdvyrdealnnrfq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7k37E (E:)
mktiialsyifclalgqdlpgndnstatlclghhavpngtlvktitddqievtnatelvq
ssstgkicnnphrildgidctlidallgdphcdvfqnetwdlfverskafsncypydvpd
yaslrslvassgtlefitegftwtgvtqnggsnackrgpgsgffsrlnwltksgstypvl
nvtmpnndnfdklyiwgvhhpstnqeqtslyvqasgrvtvstrrsqqtiipnigsrpwvr
glssrisiywtivkpgdvlvinsngnliaprgyfkmrtgkssimrsdapidtcisecitp
ngsipndkpfqnvnkitygacpkyvkqntlklatgmrnvpekqtr

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37E (E:)
statlclghhavpngtlvktitddqievtnatelvqssstgkicnnphrildgidctlid
allgdphcdvfqnetwdlfverskafsncypydvpdyaslrslvassgtlefitegftwt
gvtqnggsnackrgpgsgffsrlnwltksgstypvlnvtmpnndnfdklyiwgvhhpstn
qeqtslyvqasgrvtvstrrsqqtiipnigsrpwvrglssrisiywtivkpgdvlvinsn
gnliaprgyfkmrtgkssimrsdapidtcisecitpngsipndkpfqnvnkitygacpky
vkqntlklatgmrnvpek

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7k37F (F:)
glfgaiagfiengwegmidgwygfrhqnsegtgqaadlkstqaaidqingklnrviektn
ekfhqiekefsevegriqdlekyvedtkidlwsynaellvalenqhtidltdsemnklfe
ktrrqlrenaedmgngcfkiyhkcdnaciesirngtydhdvyrdealnnrfqikgvelks
gykdwilwisfaiscfllcvvllgfimwacqrgnircnicismgwshpqfekgggarggs
gggswshpqfekgf

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37F (F:)
glfgaiagfiengwegmidgwygfrhqnsegtgqaadlkstqaaidqingklnrviektn
ekfhqiekefsevegriqdlekyvedtkidlwsynaellvalenqhtidltdsemnklfe
ktrrqlrenaedmgngcfkiyhkcdnaciesirngtydhdvyrdealnnrfq

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >7k37G (G:)
qsvltqppsvsgapgqrvtisctgsssnigagyavhwyqqlpgtapkllisgnsnrpsgv
pdrfsgsksgtsaslaitglqaedeadyycqsydsslsgsvfgggtkltvlgrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37G (G:)
svltqppsvsgapgqrvtisctgssavhwyqqlpgtapkllisgnsnrpsgvpdrfsgsk
sgtsaslaitglqaedeadyycqssvfgggtkltvlgrtvaapsvfifppsdeqlksgta
svvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskadyekhk
vyacevthqglsspvtksfnrg

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >7k37I (I:)
qsvltqppsvsgapgqrvtisctgsssnigagyavhwyqqlpgtapkllisgnsnrpsgv
pdrfsgsksgtsaslaitglqaedeadyycqsydsslsgsvfgggtkltvlgrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37I (I:)
svltqppsvsgapgqrvtisctgssavhwyqqlpgtapkllisgnsnrpsgvpdrfsgsk
sgtsaslaitglqaedeadyycqssvfgggtkltvlgrtvaapsvfifppsdeqlksgta
svvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskadyekhk
vyacevthqglsspvtksfnrg

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >7k37K (K:)
qsvltqppsvsgapgqrvtisctgsssnigagyavhwyqqlpgtapkllisgnsnrpsgv
pdrfsgsksgtsaslaitglqaedeadyycqsydsslsgsvfgggtkltvlgrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >7k37K (K:)
svltqppsvsgapgqrvtisctgssavhwyqqlpgtapkllisgnsnrpsgvpdrfsgsk
sgtsaslaitglqaedeadyycqssvfgggtkltvlgrtvaapsvfifppsdeqlksgta
svvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskadyekhk
vyacevthqglsspvtksfnrg

  • Chain 'L':
    No sequence available.