PDB entry 7k2h

View 7k2h on RCSB PDB site
Description: kelch domain of human keap1 bound to nrf2 cyclic peptide, c[gdpetge]
Deposited on 2020-09-08, released 2021-04-07
The last revision was dated 2021-04-07, with a file datestamp of 2021-04-02.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KEAP1, INRF2, KIAA0132, KLHL19
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14145
      • conflict (289)
  • Chain 'B':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KEAP1, INRF2, KIAA0132, KLHL19
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: gly-asp-pro-glu-thr-gly-glu
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K2H (0-6)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7k2hA (A:)
vgrliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnns
pdgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsvery
eperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitam
ntirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmkhrrsalgitvhq
griyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavtmepsrkqidqqnct
c

    Sequence, based on observed residues (ATOM records):
    >7k2hA (A:)
liytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnspdg
ntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsveryepe
rdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamnti
rsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmkhrrsalgitvhqgri
yvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavtmepsr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7k2hB (B:)
vgrliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnns
pdgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsvery
eperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitam
ntirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmkhrrsalgitvhq
griyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavtmepsrkqidqqnct
c

    Sequence, based on observed residues (ATOM records):
    >7k2hB (B:)
liytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnspdg
ntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsveryepe
rdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamnti
rsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmkhrrsalgitvhqgri
yvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records:
    >7k2hP (P:)
gdpetge