PDB entry 7k2f

View 7k2f on RCSB PDB site
Description: kelch domain of human keap1 bound to nrf2 cyclic peptide, c[gaeetge]
Deposited on 2020-09-08, released 2021-04-07
The last revision was dated 2021-04-07, with a file datestamp of 2021-04-02.
Experiment type: XRAY
Resolution: 2.37 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KEAP1, INRF2, KIAA0132, KLHL19
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Nrf2 cyclic peptide,c[GAEETGE]
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 7K2F (0-6)
  • Chain 'X':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KEAP1, INRF2, KIAA0132, KLHL19
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7k2fA (A:)
mgsshhhhhhssggenlyfqghmkptqvmpsrapkvgrliytaggyfrqslsyleaynps
dgtwlrladlqvprsglagcvvggllyavggrnnspdgntdssaldcynpmtnqwspcap
msvprnrigvgvidghiyavggshgcihhnsveryeperdewhlvapmltrrigvgvavl
nrllyavggfdgtnrlnsaecyypernewrmitamntirsgagvcvlhnciyaaggydgq
dqlnsverydvetetwtfvapmkhrrsalgitvhqgriyvlggydghtfldsvecydpdt
dtwsevtrmtsgrsgvgvavtmepsrkqidqqnsts

    Sequence, based on observed residues (ATOM records):
    >7k2fA (A:)
grliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamn
tirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmkhrrsalgitvhqg
riyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >7k2fC (C:)
gaeetge

  • Chain 'X':
    Sequence, based on SEQRES records:
    >7k2fX (X:)
mgsshhhhhhssggenlyfqghmkptqvmpsrapkvgrliytaggyfrqslsyleaynps
dgtwlrladlqvprsglagcvvggllyavggrnnspdgntdssaldcynpmtnqwspcap
msvprnrigvgvidghiyavggshgcihhnsveryeperdewhlvapmltrrigvgvavl
nrllyavggfdgtnrlnsaecyypernewrmitamntirsgagvcvlhnciyaaggydgq
dqlnsverydvetetwtfvapmkhrrsalgitvhqgriyvlggydghtfldsvecydpdt
dtwsevtrmtsgrsgvgvavtmepsrkqidqqnsts

    Sequence, based on observed residues (ATOM records):
    >7k2fX (X:)
grliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamn
tirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmkhrrsalgitvhqg
riyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt