PDB entry 7k0w

View 7k0w on RCSB PDB site
Description: The crystal structure of the 2009/H1N1/California PA endonuclease (construct with truncated loop 51-72) in complex with Baloxavir acid
Class: viral protein, hydrolase
Keywords: hydrolase, virus, nuclease, cap-snatching, VIRAL PROTEIN
Deposited on 2020-09-06, released 2020-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein
    Species: Influenza A virus (strain swl A/California/04/2009 H1N1) [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (20-End)
      • expression tag (17-19)
      • linker (70-72)
    Domains in SCOPe 2.08: d7k0wa1, d7k0wa2
  • Heterogens: E4Z, MN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k0wA (A:)
mgsshhhhhhssglvprgshmedfvrqcfnpmivelaekamkeygedpkietnkfaaict
hlevcfmysdggskhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfie
igvtrrevhiyylekankiksekthihifsftgeematkadytldeesrariktrlftir
qemasrslwdsfrqser

    Sequence, based on observed residues (ATOM records): (download) 
    >7k0wA (A:)
gshmedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdggskhrf
eiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekan
kiksekthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqse