PDB entry 7k01

View 7k01 on RCSB PDB site
Description: structure of tfiih in tfiih/rad4-rad23-rad33 dna opening complex
Deposited on 2020-09-02, released 2021-07-28
The last revision was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: EM
Resolution: 3.9 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '0':
    Compound: DNA repair helicase rad3
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain '1':
    Compound: General transcription and DNA repair factor IIH subunit TFB1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain '2':
    Compound: General transcription and DNA repair factor IIH subunit TFB2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain '4':
    Compound: General transcription and DNA repair factor IIH subunit TFB4
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain '5':
    Compound: RNA polymerase II transcription factor B subunit 5
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain '6':
    Compound: General transcription and DNA repair factor IIH subunit SSL1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain '7':
    Compound: DNA repair helicase RAD25
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, SF4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain '0':
    Sequence, based on SEQRES records:
    >7k010 (0:)
mkfyiddlpvlfpypkiypeqynymcdikktldvggnsilempsgtgktvsllsltiayq
mhypehrkiiycsrtmseiekalvelenlmdyrtkelgyqedfrglgltsrknlclhpev
skerkgtvvdekcrrmtngqakrkleedpeanvelceyhenlynievedylpkgvfsfek
llkyceektlcpyfivrrmislcniiiysyhylldpkiaervsnevskdsivifdeahni
dnvcieslsldlttdalrratrganalderisevrkvdsqklqdeyeklvqglhsadilt
dqeepfvetpvlpqdllteaipgnirraehfvsflkrlieylktrmkvlhvisetpksfl
qhlkqltfierkplrfcserlsllvrtlevtevedftalkdiatfatlistyeegfllii
epyeienaavpnpimrftcldasiaikpvferfssviitsgtispldmyprmlnfktvlq
ksyamtlakksflpmiitkgsdqvaissrfeirndpsivrnygsmlvefakitpdgmvvf
fpsylymesivsmwqtmgildevwkhklilvetpdaqetslaletyrkacsngrgaills
vargkvsegidfdhqygrtvlmigipfqytesrilkarlefmrenyrirendflsfdamr
haaqclgrvlrgkddygvmvladrrfsrkrsqlpkwiaqglsdadlnlstdmaisntkqf
lrtmaqptdpkdqegvsvwsyedlikhqnsrkdqggfienenkegeqdededediemq

    Sequence, based on observed residues (ATOM records):
    >7k010 (0:)
mkfyiddlpvlfpypkiypeqynymcdikktldvggnsilempsgtgktvsllsltiayq
mhypehrkiiycsrtmseiekalvelenlmdyrtkelgyqedfrglgltsrknlclhpev
skerkgtvvdekcrrmtngqakrkleedpeanvelceyhenlynievedylpkgvfsfek
llkyceektlcpyfivrrmislcniiiysyhylldpkiaervsnevskdsivifdeahni
dnvcieslsldlttdalrratrganalderisevrkvdsqklqdeyeklvqglhsadilt
dqeepfvetpvlpqdllteaipgnirraehfvsflkrlieylktrmkvlhvisetpksfl
qhlkqltfierkplrfcserlsllvrtlevtevedftalkdiatfatlistyeegfllii
epyeienaavpnpimrftcldasiaikpvferfssviitsgtispldmyprmlnfktvlq
ksyamtlakksflpmiitkgsdqvaissrfeirndpsivrnygsmlvefakitpdgmvvf
fpsylymesivsmwqtmgildevwkhklilvetpdaqetslaletyrkacsngrgaills
vargkvsegidfdhqygrtvlmigipfqytesrilkarlefmrenyrirendflsfdamr
haaqclgrvlrgkddygvmvladrrfsrkrsqlpkwiaqglsdadlnlstdmaisntkqf
lrtmaqptdpkdqegvsvwsyedlikhqnsrkdq

  • Chain '1':
    Sequence, based on SEQRES records:
    >7k011 (1:)
mshsgaaifekvsgiiainedvspaeltwrstdgdkvhtvvlstidklqatpassekmml
rligkvdeskkrkdnegnevvpkpqrhmfsfnnrtvmdnikmtlqqiisrykdadiyeek
rrreesaqhtetpmssssvtagtptphldtpqlnngaplintaklddslskeklltnlkl
qqsllkgnkvlmkvfqetvinaglppsefwstripllrafalstsqkvgpynvlstikpv
assenkvnvnlsrekilnifenypivkkaytdnvpknfkepefwarffssklfrklrgek
imqndrgdviidryltldqefdrkdddmllhpvkkiidldgniqddpvvrgnrpdftmqp
gvdingnsdgtvdilkgmnrlsekmimalkneysrtnlqnksnitndeededndernelk
iddlnesyktnyaiihlkrnahekttdndakssadsiknadlkvsnqqmlqqlslvmdnl
inkldlnqvvpnnevsnkinkrvitaikinakqakhnnvnsalgsfvdntsqanelevks
tlpidllescrmlhttcceflkhfyihfqsgeqkqastvkklynhlkdcieklnelfqdv
lngdgesmsntctaylkpvlnsitlathkydeyfneynnnsn

    Sequence, based on observed residues (ATOM records):
    >7k011 (1:)
slskeklltnlklqqsllkgnkvlmkvfqetvinaglppsefwstripllrafalstsqk
vgpynvlstikpvassenkvnvnlsrekilnifenypivkkaytdnvpknfkepefwarf
fssklfrklrgekimqndrgdviidryltldqefdrkdddmllhpvkkiidldgniqddp
vvrgnrpdsdgtvdilkgmnrlsekmimalkneysnqqmlqqlslvmdnlinkldlnqvv
pnnevsnkinkrvitaikinakqakhnnvevkstlpidllescrmlhttcceflkhfyih
qkqastvkklynhlkdcieklnelfqdvlngdgesmsntctaylkpvlnsitlathkyde
yfneynn

  • Chain '2':
    Sequence, based on SEQRES records:
    >7k012 (2:)
msdyslkhsvtqyleeipqqvqnrlytspatclaiyrilpplakffimamvfnenevpll
dldkwvnsngklqfqnaiksmkslhllipnkssgtlminlnptfkislrnaltggevqns
fgvvveenvvsldlldeysankwetilhfmvgtplakipsekvlnllkhsklmeevnstg
efkitnegfqfllqeinsqlwtlllqylkmietskmdlvdvlhfifmlgalevgkaykid
alsetqrimlqdmrdyglvfqkhsndsifyptklalmltsdtktirsasnamdsvlrqnr
eepsvnedgangksttdittsddlnkaglknqdipdgslivetnfkiysysnsplqiavl
slfvhlkarfvnmvlgqitresirraltngitadqiiaylethahpqmrrlaeeklekkl
eldpnckeplqvlpptvvdqirlwqleldrvityegslysdfetsqeynllskyaqdigv
llwkddkkkkffiskegnsqvldfakrklkkkq

    Sequence, based on observed residues (ATOM records):
    >7k012 (2:)
khsvtqyleeipqqvqnrlytspatclaiyrilpplakffimamvfnenevplldldkwv
nsngklqfqnaiksmkslhllipnkssgtlminlnptfkislrnaltggevqnsfgvvve
envvsldlldeysankwetilhfmvgtplakipsekvlnllkhsklmeevnstgefkitn
egfqfllqeinsqlwtlllqylkmietskmdlvdvlhfifmlgalevgkaykidalsetq
rimlqdmrdyglvfqkhsndsifyptklalmltsdtktirglknqdipdgslivetnfki
ysysnsplqiavlslfvhlkarfvnmvlgqitresirraltngitadqiiaylethahpq
mrrlaeeklekkleldpnckeplqvlpptvvdqirlwqleldrvityegslysdfetsqe
ynllskyaqdigvllwkddkkkkffiskegnsqvldfakr

  • Chain '4':
    Sequence, based on SEQRES records:
    >7k014 (4:)
mdaisdptfkharsrkqvteespslltviieiapklwttfdeegnekgsiikvlealivf
lnahlafnsankvaviaaysqgikylypestsalkasesenktrsdlkiinsdmyrrfrn
vdetlveeiyklfelekkqieqnsqrstlagamsagltyvnriskesvttslksrllvlt
cgsgsskdeifqyipimncifsatkmkcpidvvkiggskestflqqttdatngvylhves
tegliqylatamfidpslrpiivkpnhgsvdfrtscyltgrvvavgficsvclcvlsiip
pgnkcpacdsqfdehviaklkrkpvvprlkakkkvtkp

    Sequence, based on observed residues (ATOM records):
    >7k014 (4:)
spslltviieiapklwttfdeegnekgsiikvlealivflnahlafnsankvaviaaysq
gikylypestsaldmyrrfrnvdetlveeiyklfelekkqieqnsqrstlagamsaglty
vnriskesvttslksrllvltcgsgsskdeifqyipimncifsatkmkcpidvvkiggsk
estflqqttdatngvylhvestegliqylatamfidpslrpiivkpnhgsvdfrtscylt
grvvavgficsvclcvlsiippgnkcpacdsqfdehviaklkrk

  • Chain '5':
    Sequence, based on SEQRES records:
    >7k015 (5:)
mararkgalvqcdpsikalilqidakmsdivleelddthllvnpskvefvkhelnrllsk
niynpmdeeenq

    Sequence, based on observed residues (ATOM records):
    >7k015 (5:)
ararkgalvqcdpsikalilqidakmsdivleelddthllvnpskvefvkhelnrllskn
iynpmd

  • Chain '6':
    Sequence, based on SEQRES records:
    >7k016 (6:)
mapvviseseededrvaitrrtkrqvhfdgegddrvdqqqqqhssshrdrdkhvqrkkkk
rlsnrnlqgsnggyawedeikrswdlvkvddegdmaslvasivearkkrtakknitpyqr
giirsliltldcseamlekdlrpnrhamiiqyaidfvheffdqnpisqmgiiimrnglaq
lvsqvsgnpqdhidalksirkqepkgnpslqnalemarglllpvpahctrevlivfgsls
ttdpgdihqtidslvsekirvkvlglsaqvaickelckatnygdesfykilldethlkel
fneavtplpvnkinkgftlvkmgfptrifedtptfcschsklvyggyfcpnchskvcslp
tvcpccdlmlilsthlarsyhhlmplktfaevpttekfrsedcfscqsrfpilknhkngk
lltssryrcedckqefcvdcdvfiheilhncpgceskpvit

    Sequence, based on observed residues (ATOM records):
    >7k016 (6:)
kkrtakknitpyqrgiirsliltldcseamlekdlrpnrhamiiqyaidfvheffdqnpi
sqmgiiimrnglaqlvsqvsgnpqdhidalksirkqepkgnpslqnalemarglllpvpa
hctrevlivfgslsttdpgdihqtidslvsekirvkvlglsaqvaickelckatnygdes
fykilldethlkelfneavtplpvnkinkgftlvkmgfptrifedtptfcschsklvygg
yfcpnchskvcslptvcpccdlmlilsthlarsyhhlmplktfaevpttekfrsedcfsc
qsrfpilknhkngklltssryrcedckqefcvdcdvfiheilhncpgcesk

  • Chain '7':
    Sequence, based on SEQRES records:
    >7k017 (7:)
mtdvegyqpkskgkifpdmgesffssdedspatdaeidenyddnretsegrgerdtgamv
tglkkprkktkssrhtaadssmnqmdakdkallqdtnsdipadfvpdsvsgmfrshdfsy
lrlrpdhasrplwispsdgriilesfsplaeqaqdflvtiaepisrpshiheykitaysl
yaavsvgletddiisvldrlskvpvaesiinfikgatisygkvklvikhnryfvettqad
ilqmllndsvigplridsdhqvqppedvlqqqlqqtagkpatnvnpndveavfsaviggd
nereeedddidavhsfeianesvevvkkrcqeidypvleeydfrndhrnpdldidlkpst
qirpyqekslskmfgngrarsgiivlpcgagktlvgitaactikksvivlctssvsvmqw
rqqflqwctlqpencavftsdnkemfqtesglvvstysmvantrnrshdsqkvmdfltgr
ewgfiildevhvvpaamfrrvvstiaahaklgltatlvreddkigdlnfligpklyeanw
melsqkghianvqcaevwcpmtaefyqeylretarkrmllyimnptkfqacqfliqyher
rgdkiivfsdnvyalqeyalkmgkpfiygstpqqermnilqnfqyndqintiflskvgdt
sidlpeatcliqisshygsrrqeaqrlgrilrakrrndegfnaffyslvskdtqemyyst
krqaflvdqgyafkvithlhgmenipnlayasprerrellqevllkneeaagievgddad
nsvgrgsnghkrfkskavrgegslsglaggedmaymeystnknkelkehhplirkmyykn
lkk

    Sequence, based on observed residues (ATOM records):
    >7k017 (7:)
padfvpdsvsgmfrshdfsylrlrpdhasrplwispsdgriilesfsplaeqaqdflvti
aepisrpshiheykitayslyaavsvgletddiisvldrlskvpvaesiinfikgatisy
gkvklvikhnryfvettqadilqmllndsvigplridsdhqvqppedvlereeedddida
vhsfeianesvevvkkrcqeidypvleeydfrndhrnpdldidlkpstqirpyqekslsk
mfgngrarsgiivlpcgagktlvgitaactikksvivlctssvsvmqwrqqflqwctlqp
encavftsdnkemfqtesglvvstysmvantrnrshdsqkvmdfltgrewgfiildevhv
vpaamfrrvvstiaahaklgltatlvreddkigdlnfligpklyeanwmelsqkghianv
qcaevwcpmtaefyqeylretarkrmllyimnptkfqacqfliqyherrgdkiivfsdnv
yalqeyalkmgkpfiygstpqqermnilqnfqyndqintiflskvgdtsidlpeatcliq
isshygsrrqeaqrlgrilrakrrndegfnaffyslvskdtqemyystkrqaflvdqgya
fkvithlhgmenipnlayasprerrellqevllk