PDB entry 7jyy

View 7jyy on RCSB PDB site
Description: crystal structure of sars-cov-2 nsp16/10 heterodimer in complex with (m7gpppa)pupupapapa (cap-0) and s-adenosylmethionine (sam).
Deposited on 2020-09-01, released 2020-09-16
The last revision was dated 2021-12-15, with a file datestamp of 2021-12-10.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2'-O-methyltransferase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (2-299)
      • expression tag (0-1)
  • Chain 'B':
    Compound: non-structural protein 10
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (2-140)
      • expression tag (0-1)
  • Chain 'C':
    Compound: 2'-O-methyltransferase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (2-299)
      • expression tag (0-1)
  • Chain 'D':
    Compound: non-structural protein 10
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (2-140)
      • expression tag (0-1)
  • Chain 'E':
    Compound: RNA (5'-d(*(m7g))-r(p*ap*up*up*a)-3')
    Species: Severe acute respiratory syndrome coronavirus 2, synthetic [TaxId:2697049]
  • Chain 'F':
    Compound: RNA (5'-d(*(m7g))-r(p*ap*up*up*a)-3')
    Species: Severe acute respiratory syndrome coronavirus 2, synthetic [TaxId:2697049]
  • Heterogens: M7G, MG, SAM, ZN, NA, CL, FMT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >7jyyA (A:)
snssqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntlt
lavpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcatv
htankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswna
dlyklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpiq
lssyslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvnn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7jyyB (B:)
snagnatevpanstvlsfcafavdaakaykdylasggqpitncvkmlcthtgtgqaitvt
peanmdqesfggascclycrchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvct
vcgmwkgygcscdqlrepmlq

    Sequence, based on observed residues (ATOM records):
    >7jyyB (B:)
stvlsfcafavdaakaykdylasggqpitncvkmlcthtgtgqaitvtpeanmdqesfgg
ascclycrchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvctvcgmwkgygcsc
dqlrepmlq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7jyyC (C:)
snssqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntlt
lavpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcatv
htankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswna
dlyklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpiq
lssyslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvnn

    Sequence, based on observed residues (ATOM records):
    >7jyyC (C:)
ssqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntltla
vpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcatvht
ankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswnadl
yklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpiqls
syslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvn

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7jyyD (D:)
snagnatevpanstvlsfcafavdaakaykdylasggqpitncvkmlcthtgtgqaitvt
peanmdqesfggascclycrchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvct
vcgmwkgygcscdqlrepmlq

    Sequence, based on observed residues (ATOM records):
    >7jyyD (D:)
cafavdaakaykdylasggqpitncvkmlcthtgtgqaitvtpeanmdqesfggasccly
crchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvctvcgmwkgygcscd

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.