PDB entry 7jxe

View 7jxe on RCSB PDB site
Description: Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Class: immune system
Keywords: fusion protein, neutralizing antibody, sarbecovirus, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID, IMMUNE SYSTEM
Deposited on 2020-08-27, released 2020-10-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: S2X35 antigen-binding (Fab) fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7JXE (0-230)
    Domains in SCOPe 2.08: d7jxeh_
  • Chain 'L':
    Compound: S2X35 antigen-binding (Fab) fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7JXE (Start-218)
    Domains in SCOPe 2.08: d7jxel1, d7jxel2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7jxeH (H:)
qvqlvqsgaevkkpgasvkvsckasgytftnygiswvrqapgqglewmgwisaykgntny
aqklqgrvtmttdtststaymelrslrsddtavyycarpdyqvlgydfwigyygmdvwgq
gttvivssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >7jxeL (L:)
qsvltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliygntnrpsgv
pdrfsgsksgtsaslaitglqaedeadyycqsydsslsgsevvfgggtkltvlgqpkaap
svtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkya
assylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >7jxeL (L:)
svltqppsvsgapgqrvtisctgsssnigagydvhwyqqlpgtapklliygntnrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydsslsevvfgggtkltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs