PDB entry 7juq

View 7juq on RCSB PDB site
Description: crystal structure of ksr2:mek1 in complex with adp
Deposited on 2020-08-20, released 2020-09-30
The last revision was dated 2020-12-30, with a file datestamp of 2020-12-25.
Experiment type: XRAY
Resolution: 3.22 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: kinase suppressor of ras 2
    Species: Homo sapiens [TaxId:9606]
    Gene: KSR2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Dual specificity mitogen-activated protein kinase kinase 1
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: MAP2K1, MEK1, PRKMK1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ADP, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7juqB (B:)
msyyhhhhhhdydipttenlyfqgaemnlsllsarsfprkasqtsiflqewdipfeqlei
geligkgrfgqvyhgrwhgevairlidierdnedqlkafkrevmayrqtrhenvvlfmga
cmspphlaiitslckgrtlysvvrdakivldvnktrqiaqeivkgmgylhakgilhkdlk
sknvfydngkvvitdfglfsisgvlqagrredklriqngwlchlapeiirqlspdteedk
lpfskhsdvfalgtiwyelharewpfktqpaeaiiwqmgtgmkpnlsqigmgkeisdill
fcwafeqeerptftklmdmleklpkrnrrlshpghfwksael

    Sequence, based on observed residues (ATOM records):
    >7juqB (B:)
tsiflqewdipfeqleigeligkgrfgqvyhgrwgevairlidierdnedqlkafkrevm
ayrqtrhenvvlfmgacmspphlaiitslckgrtlysvvrdakivldvnktrqiaqeivk
gmgylhakgilhkdlksknvfydngkvvitdfglfsisgvlqredklriqngwlchlape
iirqlspdteedklpfskhsdvfalgtiwyelharewpfktqpaeaiiwqmgtgmkpnls
qigmgkeisdillfcwafeqeerptftklmdmleklp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7juqC (C:)
msyyhhhhhhdydipttenlyfqgakkleeleldeqqrkrleafltqkqkvgelkdddfe
kiselgagnggvvfkvshkpsglvmarklihleikpairnqiirelqvlhecnspyivgf
ygafysdgeisicmehmdggsldqvlkkagripeqilgkvsiavikgltylrekhkimhr
dvkpsnilvnsrgeiklcdfgvsgqlidsmansfvgtrsymsperlqgthysvqsdiwsm
glslvemavgrypipppdakelelmfgcqvegdaaetpprprtpgrplssygmdsrppma
ifelldyivnepppklpsavfslefqdfvnkcliknpaeradlkqlmvhafikrsdaeev
dfagwlcstiglnqpstpthaagv

    Sequence, based on observed residues (ATOM records):
    >7juqC (C:)
leldeqqrkrleafltqkqkvgelkdddfekiselvvfkvshkpsglvmarklihleikp
airnqiirelqvlhecnspyivgfygafysdgeisicmehmdggsldqvlkkagripeqi
lgkvsiavikgltylrekhkimhrdvkpsnilvnsrgeiklcdfgvsgqlidsmansfvg
trsymsperlqgthysvqsdiwsmglslvemavgrypipppdakelelmfpmaifelldy
ivnepppklpsavfslefqdfvnkcliknpaeradlkqlmvhafikrsdaeevdfagwlc
stigl