PDB entry 7jtq

View 7jtq on RCSB PDB site
Description: human complement factor b inhibited by a slow off-rate modified aptamer of 31 bases
Deposited on 2020-08-18, released 2020-12-09
The last revision was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: complement factor b
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA (32-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'C':
    Compound: complement factor b
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA (32-mer)
    Species: synthetic construct, synthetic [TaxId:32630]

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7jtqA (A:)
mgsnlspqlclmpfilgllsggvtttpwslarpqgscslegveikggsfrllqegqaley
vcpsgfypypvqtrtcrstgswstlktqdqktvrkaecraihcprphdfengeywprspy
ynvsdeisfhcydgytlrgsanrtcqvngrwsgqtaicdngagycsnpgipigtrkvgsq
yrledsvtyhcsrgltlrgsqrrtcqeggswsgtepscqdsfmydtpqevaeaflsslte
tiegvdaedghgpgeqqkrkivldpsgsmniylvldgsdsigasnftgakkclvnliekv
asygvkpryglvtyatypkiwvkvseadssnadwvtkqlneinyedhklksgtntkkalq
avysmmswpddvppegwnrtrhviilmtdglhnmggdpitvideirdllyigkdrknpre
dyldvyvfgvgplvnqvninalaskkdneqhvfkvkdmenledvfyqmidesqslslcgm
vwehrkgtdyhkqpwqakisvirpskghescmgavvseyfvltaahcftvddkehsikvs
vggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpiclpct
egttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgscerda
qyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgviswg
vvdvcknqkrqkqvpahardfhinlfqvlpwlkeklqdedlgfl

    Sequence, based on observed residues (ATOM records):
    >7jtqA (A:)
qgscslegveikggsfrllqegqaleyvcpsgfypypvqtrtcrstgswstlktktvrka
ecraihcprphdfengeywprspyynvsdeisfhcydgytlrgsanrtcqvngrwsgqta
icdngagycsnpgipigtrkvgsqyrledsvtyhcsrgltlrgsqrrtcqeggswsgtep
scqdsfmydtpqevaeaflssltetikrkivldpsgsmniylvldgsdsigasnftgakk
clvnliekvasygvkpryglvtyatypkiwvkvseadssnadwvtkqlneinyegtntkk
alqavysmmswpddvppegwnrtrhviilmtdglhnmggdpitvideirdllyigkdrkn
predyldvyvfgvgplvnqvninalaskkdneqhvfkvkdmenledvfyqmidesqslsl
cgmvwehrkgtdyhkqpwqakisvirpskghescmgavvseyfvltaahcftvddkehsi
kvsvggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpicl
pctegttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgsce
rdaqyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgvi
swgvvdvcknkqvpahardfhinlfqvlpwlkeklqdedlgfl

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7jtqC (C:)
mgsnlspqlclmpfilgllsggvtttpwslarpqgscslegveikggsfrllqegqaley
vcpsgfypypvqtrtcrstgswstlktqdqktvrkaecraihcprphdfengeywprspy
ynvsdeisfhcydgytlrgsanrtcqvngrwsgqtaicdngagycsnpgipigtrkvgsq
yrledsvtyhcsrgltlrgsqrrtcqeggswsgtepscqdsfmydtpqevaeaflsslte
tiegvdaedghgpgeqqkrkivldpsgsmniylvldgsdsigasnftgakkclvnliekv
asygvkpryglvtyatypkiwvkvseadssnadwvtkqlneinyedhklksgtntkkalq
avysmmswpddvppegwnrtrhviilmtdglhnmggdpitvideirdllyigkdrknpre
dyldvyvfgvgplvnqvninalaskkdneqhvfkvkdmenledvfyqmidesqslslcgm
vwehrkgtdyhkqpwqakisvirpskghescmgavvseyfvltaahcftvddkehsikvs
vggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpiclpct
egttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgscerda
qyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgviswg
vvdvcknqkrqkqvpahardfhinlfqvlpwlkeklqdedlgfl

    Sequence, based on observed residues (ATOM records):
    >7jtqC (C:)
qgscslegveikggsfrllqegqaleyvcpsgfypypvqtrtcrstgswstlktktvrka
ecraihcprphdfengeywprspyynvsdeisfhcydgytlrgsanrtcqvngrwsgqta
icdngagycsnpgipigtrkvgsqyrledsvtyhcsrgltlrgsqrrtcqeggswsgtep
scqdsfmydtpqevaeaflssltetikrkivldpsgsmniylvldgsdsigasnftgakk
clvnliekvasygvkpryglvtyatypkiwvkvseadssnadwvtkqlneinyegtntkk
alqavysmmswpddvppegwnrtrhviilmtdglhnmggdpitvideirdllyigkdrkn
predyldvyvfgvgplvnqvninalaskkdneqhvfkvkdmenledvfyqmidesqslsl
cgmvwehrkgtdyhkqpwqakisvirpskghescmgavvseyfvltaahcftvddkehsi
kvsvggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpicl
pctegttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgsce
rdaqyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgvi
swgvvdvcknkqvpahardfhinlfqvlpwlkeklqdedlgfl

  • Chain 'D':
    No sequence available.