PDB entry 7jpe

View 7jpe on RCSB PDB site
Description: Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with m7GpppA Cap-0 and SAM Determined by Fixed-Target Serial Crystallography
Class: viral protein
Keywords: SARS CoV-2, Serial Crystallography, Methyltransferase, m7GpppA, Cap-0, S-adenosylhomomethionine, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, VIRAL PROTEIN
Deposited on 2020-08-07, released 2020-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2'-O-methyltransferase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-300)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7jpea1, d7jpea2
  • Chain 'B':
    Compound: non-structural protein 10
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-141)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7jpeb_
  • Heterogens: 8NK, GTA, SAM, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7jpeA (A:)
snassqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntl
tlavpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcat
vhtankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswn
adlyklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpi
qlssyslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvn
n

    Sequence, based on observed residues (ATOM records): (download) 
    >7jpeA (A:)
assqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntltl
avpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcatvh
tankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswnad
lyklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpiql
ssyslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvnn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7jpeB (B:)
snaagnatevpanstvlsfcafavdaakaykdylasggqpitncvkmlcthtgtgqaitv
tpeanmdqesfggascclycrchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvc
tvcgmwkgygcscdqlrepmlq

    Sequence, based on observed residues (ATOM records): (download) 
    >7jpeB (B:)
afavdaakaykdylasggqpitncvkmlcthtgtgqaitvtpeanmdqesfggascclyc
rchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvctvcgmwkgygcscdq