PDB entry 7jou

View 7jou on RCSB PDB site
Description: crystal structure of rho-associated protein kinase 1 (rock1) in complex with a phenylpyrazole amide inhibitor
Deposited on 2020-08-07, released 2020-09-02
The last revision was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 3.32 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Rho-associated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ROCK1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: VFS, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7jouA (A:)
ghmsfetrfekmdnllrdpksevnsdclldgldalvydldfpalrknknidnflsrykdt
inkirdlrmkaedyevvkvigrgafgevqlvrhkstrkvyamkllskfemikrsdsaffw
eerdimafanspwvvqlfyafqddrylymvmeympggdlvnlmsnydvpekwarfytaev
vlaldaihsmgfihrdvkpdnmlldksghlkladfgtcmkmnkegmvrcdtavgtpdyis
pevlksqggdgyygrecdwwsvgvflyemlvgdtpfyadslvgtyskimnhknsltfpdd
ndiskeaknlicafltdrevrlgrngveeikrhlffkndqwawetlrdtvapvvpdlssd
idtsnfddleedkgeeetfpipkafvgnqlpfvgftyysnrrylssanpndnr

    Sequence, based on observed residues (ATOM records):
    >7jouA (A:)
trfekmdnllrdpksevnsdclldgldalvydldfpalrknknidnflsrykdtinkird
lrmkaedyevvkvigrgafgevqlvrhkstrkvyamkllskfemikrsdsaffweerdim
afanspwvvqlfyafqddrylymvmeympggdlvnlmsnydvpekwarfytaevvlalda
ihsmgfihrdvkpdnmlldksghlkladfgtcmkmnkegmvrcdtavgtpdyispevlks
qggdgyygrecdwwsvgvflyemlvgdtpfytyskimnhknsltfpddndiskeaknlic
afltdrevrlgrngveeikrhlffkndqwawetlrdtvapvvpdlssdidtsnfddleed
kgeeetfpipkafvgnqlpfvgftyysn