PDB entry 7jl8

View 7jl8 on RCSB PDB site
Description: human primpol extending from the correct primer base c opposite the 8- oxoguanine lesion
Deposited on 2020-07-29, released 2021-06-30
The last revision was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed primase/polymerase protein
    Species: Homo sapiens [TaxId:9606]
    Gene: PRIMPOL, CCDC111
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA-directed primase/polymerase protein
    Species: Homo sapiens [TaxId:9606]
    Gene: PRIMPOL, CCDC111
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA (5'-d(p*ap*tp*(8og)p*cp*cp*tp*ap*cp*cp*ap*cp*a)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'D':
    Compound: DNA (5'-d(p*gp*tp*gp*gp*tp*ap*gp*gp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'G':
    Compound: DNA (5'-d(p*ap*tp*(8og)p*cp*cp*tp*ap*cp*cp*ap*cp*a)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'H':
    Compound: DNA (5'-d(p*gp*tp*gp*gp*tp*ap*gp*gp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: 8OG, DTP, CA, GOL, EDO, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7jl8A (A:)
mnrkweaklkqieerashyerkplssvyrprlskpeeppsiwrlfhrqaqafnfvkscke
dvhvfaleckvgdgqriylvttyaefwfyyksrknllhcyevipenavcklyfdlefnkp
anpgadgkkmvallieyvckalqelygvncsaedvlnldsstdekfsrhlifqlhdvafk
dnihvgnflrkilqpaldllgsedddsapettghgfphfseaparqgfsfnkmftekate
eswtsnskklerlgsaeqsspdlsflvvknnmgekhlfvdlgvytrnrnfrlyksskigk
rvalevtednkffpiqskdvsdeyqyflsslvsnvrfsdtlriltcepsqnkqk

    Sequence, based on observed residues (ATOM records):
    >7jl8A (A:)
mnrkweaklkqieeraseeppsiwrlfhrqaqafnfvksckedvhvfaleckvgdgqriy
lvttyaefwfyyksrknllhcyevipenavcklyfdlefnkpanpgadgkkmvallieyv
ckalqelygvncsaedvlnldsstdekfsrhlifqlhdvafkdnihvgnflrkilqpald
llpdlsflvvknnmgekhlfvdlgvytrnrnfrlyksskigkrvalevtednkffpiqsk
dvsdeyqyflsslvsnvrfsdtlriltcep

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7jl8B (B:)
mnrkweaklkqieerashyerkplssvyrprlskpeeppsiwrlfhrqaqafnfvkscke
dvhvfaleckvgdgqriylvttyaefwfyyksrknllhcyevipenavcklyfdlefnkp
anpgadgkkmvallieyvckalqelygvncsaedvlnldsstdekfsrhlifqlhdvafk
dnihvgnflrkilqpaldllgsedddsapettghgfphfseaparqgfsfnkmftekate
eswtsnskklerlgsaeqsspdlsflvvknnmgekhlfvdlgvytrnrnfrlyksskigk
rvalevtednkffpiqskdvsdeyqyflsslvsnvrfsdtlriltcepsqnkqk

    Sequence, based on observed residues (ATOM records):
    >7jl8B (B:)
ppsiwrlfhrqaqafnfvksckedvhvfaleckvgdgqriylvttyaefwfyyksrknll
hcyevipenavcklyfdlefnkpanpgadgkkmvallieyvckalqelygvncsaedvln
ldsstdekfsrhlifqlhdvafkdnihvgnflrkilqpaldlldlsflvvknnmgekhlf
vdlgvytrnrnfrlyksskigkrvalevtednkffpiqskdvsdeyqyflsslvsnvrfs
dtlriltcep

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.