PDB entry 7jkm

View 7jkm on RCSB PDB site
Description: REGN1 Human Fab in complex with anti-Kappa VHH domain
Class: immune system
Keywords: Fab, chaperone, IMMUNE SYSTEM
Deposited on 2020-07-28, released 2021-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-08-04, with a file datestamp of 2021-07-30.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: REGN1 Antibody Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7JKM (0-224)
    Domains in SCOPe 2.08: d7jkmh_
  • Chain 'K':
    Compound: anti-Kappa VHH domain nanobody
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 7JKM (0-120)
    Domains in SCOPe 2.08: d7jkmk_
  • Chain 'L':
    Compound: REGN1 Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7JKM (0-214)
    Domains in SCOPe 2.08: d7jkml_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7jkmH (H:)
evhlvesggglvqpgrslrlscaasgftfddytmhwvrqapgkglewvsdiswnsgsigy
adsvkgrftvsrdnaknslylqmnslrgedtaiyycakdmsgyghygkygmdvwgqgttv
tvssaatkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpcv
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepa

    Sequence, based on observed residues (ATOM records): (download) 
    >7jkmH (H:)
evhlvesggglvqpgrslrlscaasgftfddytmhwvrqapgkglewvsdiswnsgsigy
adsvkgrftvsrdnaknslylqmnslrgedtaiyycakdmsgyghygkygmdvwgqgttv
tvssaatkgpsvfplapggtaalgclvkdyfpepvtvswnsgaltsgvhtfpcvlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepa

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >7jkmK (K:)
evqlqesggglvqpggslrlscaasgrtisryamswfrqapgkerefvatarrsgdgafy
adsvqgrftvsrddakntvylqmnslkpedtavyycaidsdtfysgsydywgqgtqvtvs
a

    Sequence, based on observed residues (ATOM records): (download) 
    >7jkmK (K:)
evqlqesggglvqpggslrlscaasgrtisryamswfrqapgkerefvatarrsgdgafy
adsvqgrftvsrddakntvylqmnslkpedtavyycaidsdtfysgsydywgqgtqvtvs

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >7jkmL (L:)
diqmtqspillsasvgdrvtitcrasqsirsylnwyqqrtngsprlliyaasslqsgvps
rfsgsgsgtdftltinslqpddeadyycqqtysnppitfgagtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >7jkmL (L:)
diqmtqspillsasvgdrvtitcrasqsirsylnwyqqrtngsprlliyaasslqsgvps
rfsgsgsgtdftltinslqpddeadyycqqtysnppitfgagtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrge