PDB entry 7jhp

View 7jhp on RCSB PDB site
Description: Crystal structure of HRas in complex with the Ras-binding and cysteine-rich domains of CRaf-kinase
Class: signaling protein
Keywords: Ras, Raf, RBD, CRD, SIGNALING PROTEIN
Deposited on 2020-07-21, released 2020-08-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 2.77 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (0-165)
      • engineered mutation (96)
    Domains in SCOPe 2.07: d7jhpa_
  • Chain 'C':
    Compound: raf proto-oncogene serine/threonine-protein kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: RAF1, RAF
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GNP, MG, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >7jhpA (A:)
    mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
    qeeysamrdqymrtgegflcvfainntksfedihqyceqikrvkdsddvpmvlvgnkcdl
    aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh
    

  • Chain 'C':
    No sequence available.