PDB entry 7jhe

View 7jhe on RCSB PDB site
Description: Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with 2'-O-methylated m7GpppA Cap-1 and SAH Determined by Fixed-Target Serial Crystallography
Class: viral protein
Keywords: SARS CoV-2, Serial Crystallography, Methyltransferase, m7GpppA, Cap-1, S-adenosylhomocysteine, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, VIRAL PROTEIN
Deposited on 2020-07-20, released 2020-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2'-O-methyltransferase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-300)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7jhea1, d7jhea2
  • Chain 'B':
    Compound: non-structural protein 10
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-141)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7jheb_
  • Heterogens: V9G, MGP, SAH, ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7jheA (A:)
snassqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntl
tlavpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcat
vhtankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswn
adlyklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpi
qlssyslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvn
n

    Sequence, based on observed residues (ATOM records): (download) 
    >7jheA (A:)
assqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntltl
avpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcatvh
tankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswnad
lyklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpiql
ssyslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvnn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7jheB (B:)
snaagnatevpanstvlsfcafavdaakaykdylasggqpitncvkmlcthtgtgqaitv
tpeanmdqesfggascclycrchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvc
tvcgmwkgygcscdqlrepmlq

    Sequence, based on observed residues (ATOM records): (download) 
    >7jheB (B:)
afavdaakaykdylasggqpitncvkmlcthtgtgqaitvtpeanmdqesfggascclyc
rchidhpnpkgfcdlkgkyvqipttcandpvgftlkntvctvcgmwkgygcscdq