PDB entry 7jfl

View 7jfl on RCSB PDB site
Description: Crystal structure of human phosphorylated IRF-3 bound to CBP
Class: immune system
Keywords: transcription factor, phosphorylation, innate immunity, IMMUNE SYSTEM
Deposited on 2020-07-17, released 2020-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-07, with a file datestamp of 2020-10-02.
Experiment type: XRAY
Resolution: 1.68 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Interferon regulatory factor 3
  Species: Homo sapiens [TaxId:9606]
  Gene: IRF3
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q14653
• Chain 'B':
  Compound: Interferon regulatory factor 3
  Species: Homo sapiens [TaxId:9606]
  Gene: IRF3
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q14653
• Chain 'C':
  Compound: creb-binding protein
  Species: Homo sapiens [TaxId:9606]
  Gene: CREBBP, CBP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q92793
  Domains in SCOPe 2.08: d7jflc_
• Chain 'D':
  Compound: creb-binding protein
  Species: Homo sapiens [TaxId:9606]
  Gene: CREBBP, CBP
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q92793
  Domains in SCOPe 2.08: d7jfld_
• Heterogens: SEP, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  Sequence, based on SEQRES records: (download)
  

  >7jflC (C:)
  salqdllrtlkspsspqqqqqvlnilksnpqlmaafikqrtakyvan
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >7jflC (C:)
  dllrtlkspsspqqqqqvlnilksnpqlmaafikqr
  

  
  
• Chain 'D':
  Sequence, based on SEQRES records: (download)
  

  >7jflD (D:)
  salqdllrtlkspsspqqqqqvlnilksnpqlmaafikqrtakyvan
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >7jflD (D:)
  alqdllrtlkspsspqqqqqvlnilksnpqlmaafikq