PDB entry 7f5o

View 7f5o on RCSB PDB site
Description: Crystal structure of PTPN2 catalytic domain
Class: hydrolase
Keywords: Protein Tyrosine Phosphatase, TCPTP, PTPN2, HYDROLASE
Deposited on 2021-06-22, released 2021-12-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-01-12, with a file datestamp of 2022-01-07.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN2, PTPT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17706 (3-304)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7f5oa1, d7f5oa2
  • Chain 'B':
    Compound: Tyrosine-protein phosphatase non-receptor type 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN2, PTPT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17706 (3-304)
      • expression tag (0-2)
  • Chain 'C':
    Compound: Tyrosine-protein phosphatase non-receptor type 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN2, PTPT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17706 (3-304)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7f5oc_
  • Heterogens: IOD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7f5oA (A:)
snampttierefeeldtqrrwqplyleirneshdyphrvakfpenrnrnryrdvspydhs
rvklqnaendyinaslvdieeaqrsyiltqgplpntcchfwlmvwqqktkavvmlnrive
kesvkcaqywptddqemlfketgfsvkllsedvksyytvhllqleninsgetrtishfhy
ttwpdfgvpespasflnflfkvresgslnpdhgpavihcsagigrsgtfslvdtclvlme
kgddinikqvllnmrkyrmgliqtpdqlrfsymaiiegakcikgdssiqkrwkelskedl
spafd

    Sequence, based on observed residues (ATOM records): (download) 
    >7f5oA (A:)
snampttierefeeldtqrrwqplyleirneshdyphrvakfpenrnrnryrdvspydhs
rvklqnaendyinaslvdieeaqrsyiltqgplpntcchfwlmvwqqktkavvmlnrive
kesvkcaqywptddqemlfketgfsvkllsedvksyytvhllqleninsgetrtishfhy
ttwpdfgvpespasflnflfkvresgslnpdhgpavihcsagigrsgtfslvdtclvlmi
nikqvllnmrkyrmgliqtpdqlrfsymaiiegakiqkrwkelskedlspafd

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7f5oC (C:)
snampttierefeeldtqrrwqplyleirneshdyphrvakfpenrnrnryrdvspydhs
rvklqnaendyinaslvdieeaqrsyiltqgplpntcchfwlmvwqqktkavvmlnrive
kesvkcaqywptddqemlfketgfsvkllsedvksyytvhllqleninsgetrtishfhy
ttwpdfgvpespasflnflfkvresgslnpdhgpavihcsagigrsgtfslvdtclvlme
kgddinikqvllnmrkyrmgliqtpdqlrfsymaiiegakcikgdssiqkrwkelskedl
spafd

    Sequence, based on observed residues (ATOM records): (download) 
    >7f5oC (C:)
pttierefeeldtqrrwqplyleirneshdyphrvakfpenrnrnryrdvspydhsrvkl
qnaendyinaslvdieeaqrsyiltqgplpntcchfwlmvwqqktkavvmlnrivekesv
kcaqywptddqemlfketgfsvkllsedvksyytvhllqleninsgetrtishfhyttwp
dfgvpespasflnflfkvresgslnpdhgpavihcsagigrsgtfslvdtclvlminikq
vllnmrkyrmgliqtpdqlrfsymaiiegakqkrwkelske