PDB entry 7ewo

View 7ewo on RCSB PDB site
Description: Crystal Structure of D67A, E68P double mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae
Class: transferase
Keywords: Evolution, Cysteine Synthase, Protein-Protein interaction, TRANSFERASE
Deposited on 2021-05-25, released 2021-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-23, with a file datestamp of 2021-06-18.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cysteine synthase
    Species: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [TaxId:71421]
    Gene: cysK, HI_1103
    Database cross-references and differences (RAF-indexed):
    • Uniprot P45040 (34-End)
      • engineered mutation (100-101)
    Domains in SCOPe 2.08: d7ewoa_
  • Heterogens: LLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7ewoA (A:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsmaiyadnsysigntplvrlkhfghng
nvvvkiegrnpsysvkcriganmvwqaekdgtltkgkeiveptsgntgialayvaaargy
kitltmpetmslerkrllcglgvnlvltegakgmkgaiakaeeivasdpsryvmlkqfen
panpqihrettgpeiwkdtdgkvdvvvagvgtggsitgisraikldfgkqitsvavepve
spvisqtlageevkpgphkiqgigagfipknldlsiidrvetvdsdtalatarrlmaeeg
ilagissgaavaaadrlaklpefadklivvilpsaserylstalfegieg

    Sequence, based on observed residues (ATOM records): (download) 
    >7ewoA (A:)
maiyadnsysigntplvrlkhfghngnvvvkiegrnpsysvkcriganmvwqaekdgtlt
kgkeiveptsgntgialayvaaargykitltmpetmslerkrllcglgvnlvltegmkga
iakaeeivasdpsryvmlkqfenpanpqihrettgpeiwkdtdgkvdvvvagvgtggsit
gisraikldfgkqitsvavepvespvisqtlageevkpgphkiqgigagfipknldlsii
drvetvdsdtalatarrlmaeegilagissgaavaaadrlaklpefadklivvilpsas