PDB entry 7ese

View 7ese on RCSB PDB site
Description: The Crystal Structure of human DHFR from Biortus
Class: oxidoreductase
Keywords: catalytic activity, dihydrofolate reductase activity, oxidoreductase activity, OXIDOREDUCTASE
Deposited on 2021-05-10, released 2021-05-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-05-26, with a file datestamp of 2021-05-21.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: Dhfr
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7esea_
  • Heterogens: NAP, FOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7eseA (A:)
mggshhhhhhenlyfqgmvgslncivavsqnmgigkngdlpwpplrnefryfqrmtttss
vegkqnlvimgkktwfsipeknrplkgrinlvlsrelkeppqgahflsrslddalklteq
pelankvdmvwivggssvykeamnhpghlklfvtrimqdfesdtffpeidlekykllpey
pgvlsdvqeekgikykfevyeknd

    Sequence, based on observed residues (ATOM records): (download) 
    >7eseA (A:)
gslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsip
eknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssvy
keamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfev
yeknd